New insights into the molecular mechanism of the Rab GTPase Sec4p activation

BACKGROUND: Sec4p is a small monomeric Ras-related GTP-binding protein (23 kDa) that regulates polarized exocytosis in S. cerevisiae. In this study we examine the structural effects of a conserved serine residue in the P-loop corresponding to G12 in Ras. RESULTS: We show that the Sec4p residue serin...

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Detalles Bibliográficos
Autores principales: Rinaldi, Fabio C., Packer, Michael, Collins, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531439/
https://www.ncbi.nlm.nih.gov/pubmed/26263895
http://dx.doi.org/10.1186/s12900-015-0041-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531439/
https://www.ncbi.nlm.nih.gov/pubmed/26263895
http://dx.doi.org/10.1186/s12900-015-0041-5

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