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Y-27632 is associated with corticosteroid-potentiated control of pulmonary remodeling and inflammation in guinea pigs with chronic allergic inflammation

BACKGROUND: Previously, we showed that treatment with the Rho-kinase inhibitor Y-27632 was able to control airway responsiveness, inflammation, remodeling, and oxidative stress in an animal model of asthma, suggesting that this drug is beneficial in asthma. However, studies evaluating the effects of...

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Detalles Bibliográficos
Autores principales:	Pigati, Patricia Angeli, Righetti, Renato Fraga, Possa, Samantha Souza, Romanholo, Beatriz Saraiva, Rodrigues, Adriana Palmeira Dias, dos Santos, Anelize Sartori Alves, Xisto, Débora Gonçalves, Antunes, Mariana Alves, Prado, Carla Máximo, Leick, Edna Aparecida, de Arruda Martins, Milton, Rocco, Patrícia Rieken Macedo, de Fátima Lopes Calvo Tibério, Iolanda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531528/ https://www.ncbi.nlm.nih.gov/pubmed/26264367 http://dx.doi.org/10.1186/s12890-015-0073-4

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