Nail Changes During Docetaxel Containing Combination Chemotherapy

Nail toxicity following systemic chemotherapy is common. Onychopathy during the period of neutropenia following chemotherapy may cause subungual abscesses and serious infection. Despite taxoid-related toxicity being increasingly reported since 2000, there are still phase II systemic chemotherapy stu...

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Detalles Bibliográficos
Autores principales: Woo, In Sook, Shim, Kon Ho, Kim, Gi Young, Lee, Myung Ah, Kang, Jin Hyoung, Hong, Young Seon, Lee, Kyung Shik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Internal Medicine 2004
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531594/
https://www.ncbi.nlm.nih.gov/pubmed/15366647
http://dx.doi.org/10.3904/kjim.2004.19.2.132
Descripción
Sumario:Nail toxicity following systemic chemotherapy is common. Onychopathy during the period of neutropenia following chemotherapy may cause subungual abscesses and serious infection. Despite taxoid-related toxicity being increasingly reported since 2000, there are still phase II systemic chemotherapy studies using taxoid that have never mentioned nail changes. Recently, new criteria for the evaluation of nail toxicity have been suggested. The present report is the first of its kind, in Korea, to describe a case of docetaxel-associated onychopathy, which improved following a reduction in the docetaxel dose.

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