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The changes in cardiac dimensions and function in patients with end stage renal disease undergoing hemodialysis

BACKGROUND: It is absolutely necessary to evaluate cardiac function on starting and during hemodialysis in patients with end stage renal disease. In this study, we tried to determinate the changes of cardiac function associated with hemodialysis. METHODS: Twenty patients with end stage renal disease...

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Autores principales: Lee, Dong Won, Kim, Yong Beom, An, Seoung Jae, Jung, Yoo Suck, Kwak, Ihm Soo, Shin, Yung Woo, Rha, Ha Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Internal Medicine 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531672/
https://www.ncbi.nlm.nih.gov/pubmed/12164087
http://dx.doi.org/10.3904/kjim.2002.17.2.107
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author Lee, Dong Won
Kim, Yong Beom
An, Seoung Jae
Jung, Yoo Suck
Kwak, Ihm Soo
Shin, Yung Woo
Rha, Ha Yeon
author_facet Lee, Dong Won
Kim, Yong Beom
An, Seoung Jae
Jung, Yoo Suck
Kwak, Ihm Soo
Shin, Yung Woo
Rha, Ha Yeon
author_sort Lee, Dong Won
collection PubMed
description BACKGROUND: It is absolutely necessary to evaluate cardiac function on starting and during hemodialysis in patients with end stage renal disease. In this study, we tried to determinate the changes of cardiac function associated with hemodialysis. METHODS: Twenty patients with end stage renal disease, who had been in a hemodialysis program from February, 1997 to August, 1999 in Pusan National University Hospital, were enrolled. They were examined with echocardiography and gated blood pool scintigraphy on starting hemodialysis and after follow-up. The data were analyzed by paired t-test. RESULTS: The patients were 46.2±16.8 years old and male to female ratio was 8:12. The underlying diseases were diabetes mellitus (n=10), hypertension(1)), glomerulonephritis(2)) and others(1)). The duration of symptoms associated with end stage renal disease and underlying diseases was 3.4±2.6 years and the duration of hemodialysis was 13.8±7.0 months. The LVEDID, LVESID and RVC decreased significantly (−6. 10, −7.80 and −20.00%, respectively, p < 0.05) with no significant changes for LAD, IVS, PWT and EF (p > 0.05). In ten cases associated with diabetes, LVEDID decreased (−7.90%, p < 0.05). In twelve cases associated with cardiac diseases, LVEDID and LVESID decreased (−8.60 and −10.50%, respectively, p < 0.05). In four cases associated with diabetes without cardiac diseases, LAD decreased (−5.10%, p < 0.05) and in four cases associated with cardiac diseases without diabetes there were no significant changes in cardiac dimensions and EF. In seven cases associated with diabetes and cardiac diseases, LVEDID decreased (−10.50%, p < 0.05). The EF on gated blood pool scintigraphy decreased (−0.9%, p < 0.05) as a whole while it increased (5.90%, p <0.05) in the cases associated with diabetes and cardiac diseases. CONCLUSION: During the early hemodialysis stage of end stage renal disease, we found a change of concentric left ventricular hypertrophy and relatively preserved left ventricular function. Furthermore, we can expect that adequate hemodialysis – with dry weight as low as possible – may prevent progression to eccentric left ventricular hypertrophy and dilated cardiomyopathy.
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spelling pubmed-45316722015-10-02 The changes in cardiac dimensions and function in patients with end stage renal disease undergoing hemodialysis Lee, Dong Won Kim, Yong Beom An, Seoung Jae Jung, Yoo Suck Kwak, Ihm Soo Shin, Yung Woo Rha, Ha Yeon Korean J Intern Med Original Article BACKGROUND: It is absolutely necessary to evaluate cardiac function on starting and during hemodialysis in patients with end stage renal disease. In this study, we tried to determinate the changes of cardiac function associated with hemodialysis. METHODS: Twenty patients with end stage renal disease, who had been in a hemodialysis program from February, 1997 to August, 1999 in Pusan National University Hospital, were enrolled. They were examined with echocardiography and gated blood pool scintigraphy on starting hemodialysis and after follow-up. The data were analyzed by paired t-test. RESULTS: The patients were 46.2±16.8 years old and male to female ratio was 8:12. The underlying diseases were diabetes mellitus (n=10), hypertension(1)), glomerulonephritis(2)) and others(1)). The duration of symptoms associated with end stage renal disease and underlying diseases was 3.4±2.6 years and the duration of hemodialysis was 13.8±7.0 months. The LVEDID, LVESID and RVC decreased significantly (−6. 10, −7.80 and −20.00%, respectively, p < 0.05) with no significant changes for LAD, IVS, PWT and EF (p > 0.05). In ten cases associated with diabetes, LVEDID decreased (−7.90%, p < 0.05). In twelve cases associated with cardiac diseases, LVEDID and LVESID decreased (−8.60 and −10.50%, respectively, p < 0.05). In four cases associated with diabetes without cardiac diseases, LAD decreased (−5.10%, p < 0.05) and in four cases associated with cardiac diseases without diabetes there were no significant changes in cardiac dimensions and EF. In seven cases associated with diabetes and cardiac diseases, LVEDID decreased (−10.50%, p < 0.05). The EF on gated blood pool scintigraphy decreased (−0.9%, p < 0.05) as a whole while it increased (5.90%, p <0.05) in the cases associated with diabetes and cardiac diseases. CONCLUSION: During the early hemodialysis stage of end stage renal disease, we found a change of concentric left ventricular hypertrophy and relatively preserved left ventricular function. Furthermore, we can expect that adequate hemodialysis – with dry weight as low as possible – may prevent progression to eccentric left ventricular hypertrophy and dilated cardiomyopathy. Korean Association of Internal Medicine 2002-06 /pmc/articles/PMC4531672/ /pubmed/12164087 http://dx.doi.org/10.3904/kjim.2002.17.2.107 Text en Copyright © 2002 The Korean Association of Internal Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Lee, Dong Won
Kim, Yong Beom
An, Seoung Jae
Jung, Yoo Suck
Kwak, Ihm Soo
Shin, Yung Woo
Rha, Ha Yeon
The changes in cardiac dimensions and function in patients with end stage renal disease undergoing hemodialysis
title The changes in cardiac dimensions and function in patients with end stage renal disease undergoing hemodialysis
title_full The changes in cardiac dimensions and function in patients with end stage renal disease undergoing hemodialysis
title_fullStr The changes in cardiac dimensions and function in patients with end stage renal disease undergoing hemodialysis
title_full_unstemmed The changes in cardiac dimensions and function in patients with end stage renal disease undergoing hemodialysis
title_short The changes in cardiac dimensions and function in patients with end stage renal disease undergoing hemodialysis
title_sort changes in cardiac dimensions and function in patients with end stage renal disease undergoing hemodialysis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531672/
https://www.ncbi.nlm.nih.gov/pubmed/12164087
http://dx.doi.org/10.3904/kjim.2002.17.2.107
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