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Seroepidemiology of HBV Infection in South Korea, 1995 through 1999

BACKGROUND : We analyzed serologic data that were obtained from the Korea Association of Health from 1995 to 1999 to estimate the reliable prevalence of HBV in South Korea. METHODS : 603,375, 639,465, 621,476, 612,705 and 650,398 serum samples were annually tested for HBsAg. Of HBsAg positive person...

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Detalles Bibliográficos
Autores principales: Jang, Myoung Kuk, Lee, Ja Young, Lee, Jin Heon, Kim, Yong Bum, Kim, Hak Yang, Lee, Myung Seok, Park, Choong Kee, Yoo, Jae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Internal Medicine 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531730/
https://www.ncbi.nlm.nih.gov/pubmed/11769573
http://dx.doi.org/10.3904/kjim.2001.16.3.153
Descripción
Sumario:BACKGROUND : We analyzed serologic data that were obtained from the Korea Association of Health from 1995 to 1999 to estimate the reliable prevalence of HBV in South Korea. METHODS : 603,375, 639,465, 621,476, 612,705 and 650,398 serum samples were annually tested for HBsAg. Of HBsAg positive persons whose serum samples were available, HBeAg positivity was checked. RESULTS : HBsAg positivities among subjects between 6 and 19 years old were 8.2%, 3.9%, 2.1%, 2.6% and 1.3%. HBsAg positivities among subjects above 20 years old were 8.9%, 6.4%, 5.9%, 5.4% and 5.4%. The positive rates of HBeAg were 39.8 to 62.9% among subjects between 6 and 19 years old, and 18.3 to 37.9% among persons above 20 years old, in each year. In both subgroups, HBsAg positivity in the latter year was significantly lower than that in the former year (p<0.001). It also showed that HBsAg positivities among subjects between 6 and 19 years old have been significantly lower than those among subjects above 20 years old, but those of HBeAg the exact reverse of HBsAg since 1996 (p<0.001). CONCLUSIONS : It was observed that prevalence of HBV infection in the late 1990s, especially in the group between 6 and 19 years old, was conspicuously lower than that in the past. The nationwide vaccination programme might be one of the most important contributors to this tendency in Korea.