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Seroepidemiology of HBV Infection in South Korea, 1995 through 1999

BACKGROUND : We analyzed serologic data that were obtained from the Korea Association of Health from 1995 to 1999 to estimate the reliable prevalence of HBV in South Korea. METHODS : 603,375, 639,465, 621,476, 612,705 and 650,398 serum samples were annually tested for HBsAg. Of HBsAg positive person...

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Autores principales: Jang, Myoung Kuk, Lee, Ja Young, Lee, Jin Heon, Kim, Yong Bum, Kim, Hak Yang, Lee, Myung Seok, Park, Choong Kee, Yoo, Jae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Internal Medicine 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531730/
https://www.ncbi.nlm.nih.gov/pubmed/11769573
http://dx.doi.org/10.3904/kjim.2001.16.3.153
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author Jang, Myoung Kuk
Lee, Ja Young
Lee, Jin Heon
Kim, Yong Bum
Kim, Hak Yang
Lee, Myung Seok
Park, Choong Kee
Yoo, Jae Young
author_facet Jang, Myoung Kuk
Lee, Ja Young
Lee, Jin Heon
Kim, Yong Bum
Kim, Hak Yang
Lee, Myung Seok
Park, Choong Kee
Yoo, Jae Young
author_sort Jang, Myoung Kuk
collection PubMed
description BACKGROUND : We analyzed serologic data that were obtained from the Korea Association of Health from 1995 to 1999 to estimate the reliable prevalence of HBV in South Korea. METHODS : 603,375, 639,465, 621,476, 612,705 and 650,398 serum samples were annually tested for HBsAg. Of HBsAg positive persons whose serum samples were available, HBeAg positivity was checked. RESULTS : HBsAg positivities among subjects between 6 and 19 years old were 8.2%, 3.9%, 2.1%, 2.6% and 1.3%. HBsAg positivities among subjects above 20 years old were 8.9%, 6.4%, 5.9%, 5.4% and 5.4%. The positive rates of HBeAg were 39.8 to 62.9% among subjects between 6 and 19 years old, and 18.3 to 37.9% among persons above 20 years old, in each year. In both subgroups, HBsAg positivity in the latter year was significantly lower than that in the former year (p<0.001). It also showed that HBsAg positivities among subjects between 6 and 19 years old have been significantly lower than those among subjects above 20 years old, but those of HBeAg the exact reverse of HBsAg since 1996 (p<0.001). CONCLUSIONS : It was observed that prevalence of HBV infection in the late 1990s, especially in the group between 6 and 19 years old, was conspicuously lower than that in the past. The nationwide vaccination programme might be one of the most important contributors to this tendency in Korea.
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spelling pubmed-45317302015-10-02 Seroepidemiology of HBV Infection in South Korea, 1995 through 1999 Jang, Myoung Kuk Lee, Ja Young Lee, Jin Heon Kim, Yong Bum Kim, Hak Yang Lee, Myung Seok Park, Choong Kee Yoo, Jae Young Korean J Intern Med Original Article BACKGROUND : We analyzed serologic data that were obtained from the Korea Association of Health from 1995 to 1999 to estimate the reliable prevalence of HBV in South Korea. METHODS : 603,375, 639,465, 621,476, 612,705 and 650,398 serum samples were annually tested for HBsAg. Of HBsAg positive persons whose serum samples were available, HBeAg positivity was checked. RESULTS : HBsAg positivities among subjects between 6 and 19 years old were 8.2%, 3.9%, 2.1%, 2.6% and 1.3%. HBsAg positivities among subjects above 20 years old were 8.9%, 6.4%, 5.9%, 5.4% and 5.4%. The positive rates of HBeAg were 39.8 to 62.9% among subjects between 6 and 19 years old, and 18.3 to 37.9% among persons above 20 years old, in each year. In both subgroups, HBsAg positivity in the latter year was significantly lower than that in the former year (p<0.001). It also showed that HBsAg positivities among subjects between 6 and 19 years old have been significantly lower than those among subjects above 20 years old, but those of HBeAg the exact reverse of HBsAg since 1996 (p<0.001). CONCLUSIONS : It was observed that prevalence of HBV infection in the late 1990s, especially in the group between 6 and 19 years old, was conspicuously lower than that in the past. The nationwide vaccination programme might be one of the most important contributors to this tendency in Korea. Korean Association of Internal Medicine 2001-09 /pmc/articles/PMC4531730/ /pubmed/11769573 http://dx.doi.org/10.3904/kjim.2001.16.3.153 Text en Copyright © 2001 The Korean Association of Internal Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Jang, Myoung Kuk
Lee, Ja Young
Lee, Jin Heon
Kim, Yong Bum
Kim, Hak Yang
Lee, Myung Seok
Park, Choong Kee
Yoo, Jae Young
Seroepidemiology of HBV Infection in South Korea, 1995 through 1999
title Seroepidemiology of HBV Infection in South Korea, 1995 through 1999
title_full Seroepidemiology of HBV Infection in South Korea, 1995 through 1999
title_fullStr Seroepidemiology of HBV Infection in South Korea, 1995 through 1999
title_full_unstemmed Seroepidemiology of HBV Infection in South Korea, 1995 through 1999
title_short Seroepidemiology of HBV Infection in South Korea, 1995 through 1999
title_sort seroepidemiology of hbv infection in south korea, 1995 through 1999
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531730/
https://www.ncbi.nlm.nih.gov/pubmed/11769573
http://dx.doi.org/10.3904/kjim.2001.16.3.153
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