Cargando…
Seroepidemiology of HBV Infection in South Korea, 1995 through 1999
BACKGROUND : We analyzed serologic data that were obtained from the Korea Association of Health from 1995 to 1999 to estimate the reliable prevalence of HBV in South Korea. METHODS : 603,375, 639,465, 621,476, 612,705 and 650,398 serum samples were annually tested for HBsAg. Of HBsAg positive person...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Association of Internal Medicine
2001
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531730/ https://www.ncbi.nlm.nih.gov/pubmed/11769573 http://dx.doi.org/10.3904/kjim.2001.16.3.153 |
_version_ | 1782385102174552064 |
---|---|
author | Jang, Myoung Kuk Lee, Ja Young Lee, Jin Heon Kim, Yong Bum Kim, Hak Yang Lee, Myung Seok Park, Choong Kee Yoo, Jae Young |
author_facet | Jang, Myoung Kuk Lee, Ja Young Lee, Jin Heon Kim, Yong Bum Kim, Hak Yang Lee, Myung Seok Park, Choong Kee Yoo, Jae Young |
author_sort | Jang, Myoung Kuk |
collection | PubMed |
description | BACKGROUND : We analyzed serologic data that were obtained from the Korea Association of Health from 1995 to 1999 to estimate the reliable prevalence of HBV in South Korea. METHODS : 603,375, 639,465, 621,476, 612,705 and 650,398 serum samples were annually tested for HBsAg. Of HBsAg positive persons whose serum samples were available, HBeAg positivity was checked. RESULTS : HBsAg positivities among subjects between 6 and 19 years old were 8.2%, 3.9%, 2.1%, 2.6% and 1.3%. HBsAg positivities among subjects above 20 years old were 8.9%, 6.4%, 5.9%, 5.4% and 5.4%. The positive rates of HBeAg were 39.8 to 62.9% among subjects between 6 and 19 years old, and 18.3 to 37.9% among persons above 20 years old, in each year. In both subgroups, HBsAg positivity in the latter year was significantly lower than that in the former year (p<0.001). It also showed that HBsAg positivities among subjects between 6 and 19 years old have been significantly lower than those among subjects above 20 years old, but those of HBeAg the exact reverse of HBsAg since 1996 (p<0.001). CONCLUSIONS : It was observed that prevalence of HBV infection in the late 1990s, especially in the group between 6 and 19 years old, was conspicuously lower than that in the past. The nationwide vaccination programme might be one of the most important contributors to this tendency in Korea. |
format | Online Article Text |
id | pubmed-4531730 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2001 |
publisher | Korean Association of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-45317302015-10-02 Seroepidemiology of HBV Infection in South Korea, 1995 through 1999 Jang, Myoung Kuk Lee, Ja Young Lee, Jin Heon Kim, Yong Bum Kim, Hak Yang Lee, Myung Seok Park, Choong Kee Yoo, Jae Young Korean J Intern Med Original Article BACKGROUND : We analyzed serologic data that were obtained from the Korea Association of Health from 1995 to 1999 to estimate the reliable prevalence of HBV in South Korea. METHODS : 603,375, 639,465, 621,476, 612,705 and 650,398 serum samples were annually tested for HBsAg. Of HBsAg positive persons whose serum samples were available, HBeAg positivity was checked. RESULTS : HBsAg positivities among subjects between 6 and 19 years old were 8.2%, 3.9%, 2.1%, 2.6% and 1.3%. HBsAg positivities among subjects above 20 years old were 8.9%, 6.4%, 5.9%, 5.4% and 5.4%. The positive rates of HBeAg were 39.8 to 62.9% among subjects between 6 and 19 years old, and 18.3 to 37.9% among persons above 20 years old, in each year. In both subgroups, HBsAg positivity in the latter year was significantly lower than that in the former year (p<0.001). It also showed that HBsAg positivities among subjects between 6 and 19 years old have been significantly lower than those among subjects above 20 years old, but those of HBeAg the exact reverse of HBsAg since 1996 (p<0.001). CONCLUSIONS : It was observed that prevalence of HBV infection in the late 1990s, especially in the group between 6 and 19 years old, was conspicuously lower than that in the past. The nationwide vaccination programme might be one of the most important contributors to this tendency in Korea. Korean Association of Internal Medicine 2001-09 /pmc/articles/PMC4531730/ /pubmed/11769573 http://dx.doi.org/10.3904/kjim.2001.16.3.153 Text en Copyright © 2001 The Korean Association of Internal Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Jang, Myoung Kuk Lee, Ja Young Lee, Jin Heon Kim, Yong Bum Kim, Hak Yang Lee, Myung Seok Park, Choong Kee Yoo, Jae Young Seroepidemiology of HBV Infection in South Korea, 1995 through 1999 |
title | Seroepidemiology of HBV Infection in South Korea, 1995 through 1999 |
title_full | Seroepidemiology of HBV Infection in South Korea, 1995 through 1999 |
title_fullStr | Seroepidemiology of HBV Infection in South Korea, 1995 through 1999 |
title_full_unstemmed | Seroepidemiology of HBV Infection in South Korea, 1995 through 1999 |
title_short | Seroepidemiology of HBV Infection in South Korea, 1995 through 1999 |
title_sort | seroepidemiology of hbv infection in south korea, 1995 through 1999 |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531730/ https://www.ncbi.nlm.nih.gov/pubmed/11769573 http://dx.doi.org/10.3904/kjim.2001.16.3.153 |
work_keys_str_mv | AT jangmyoungkuk seroepidemiologyofhbvinfectioninsouthkorea1995through1999 AT leejayoung seroepidemiologyofhbvinfectioninsouthkorea1995through1999 AT leejinheon seroepidemiologyofhbvinfectioninsouthkorea1995through1999 AT kimyongbum seroepidemiologyofhbvinfectioninsouthkorea1995through1999 AT kimhakyang seroepidemiologyofhbvinfectioninsouthkorea1995through1999 AT leemyungseok seroepidemiologyofhbvinfectioninsouthkorea1995through1999 AT parkchoongkee seroepidemiologyofhbvinfectioninsouthkorea1995through1999 AT yoojaeyoung seroepidemiologyofhbvinfectioninsouthkorea1995through1999 |