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Acquired Hemophilia Successfully Treated With Oral Immunosuppressive Therapy

Acquired hemophilia is a rare disorder associated with serious bleeding in nonhemophilic patients. We had a 40-year-old woman who was diagnosed as acquired hemophilia with a factor VIII inhibitor level of 27.5 BU/mL. She was presented with gross hematuria and severe right shoulder pain, and was succ...

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Autores principales: Lee, Je Jung, Chung, Ik Joo, Park, Moo Rim, Yang, Duc Hwan, Cho, Sang Hee, Ryang, Dong Wook, Kim, Hyeoung Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Internal Medicine 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531764/
https://www.ncbi.nlm.nih.gov/pubmed/10992727
http://dx.doi.org/10.3904/kjim.2000.15.2.135
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author Lee, Je Jung
Chung, Ik Joo
Park, Moo Rim
Yang, Duc Hwan
Cho, Sang Hee
Ryang, Dong Wook
Kim, Hyeoung Joon
author_facet Lee, Je Jung
Chung, Ik Joo
Park, Moo Rim
Yang, Duc Hwan
Cho, Sang Hee
Ryang, Dong Wook
Kim, Hyeoung Joon
author_sort Lee, Je Jung
collection PubMed
description Acquired hemophilia is a rare disorder associated with serious bleeding in nonhemophilic patients. We had a 40-year-old woman who was diagnosed as acquired hemophilia with a factor VIII inhibitor level of 27.5 BU/mL. She was presented with gross hematuria and severe right shoulder pain, and was successfully treated with daily oral cyclophosphamide and prednisone for 2 weeks. After the remission, the doses of prednisone and cyclophosphamide were slowly decreased and she remained in complete remission without further bleeding episodes.
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spelling pubmed-45317642015-10-02 Acquired Hemophilia Successfully Treated With Oral Immunosuppressive Therapy Lee, Je Jung Chung, Ik Joo Park, Moo Rim Yang, Duc Hwan Cho, Sang Hee Ryang, Dong Wook Kim, Hyeoung Joon Korean J Intern Med Case Report Acquired hemophilia is a rare disorder associated with serious bleeding in nonhemophilic patients. We had a 40-year-old woman who was diagnosed as acquired hemophilia with a factor VIII inhibitor level of 27.5 BU/mL. She was presented with gross hematuria and severe right shoulder pain, and was successfully treated with daily oral cyclophosphamide and prednisone for 2 weeks. After the remission, the doses of prednisone and cyclophosphamide were slowly decreased and she remained in complete remission without further bleeding episodes. Korean Association of Internal Medicine 2000-07 /pmc/articles/PMC4531764/ /pubmed/10992727 http://dx.doi.org/10.3904/kjim.2000.15.2.135 Text en Copyright © 2000 The Korean Association of Internal Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Lee, Je Jung
Chung, Ik Joo
Park, Moo Rim
Yang, Duc Hwan
Cho, Sang Hee
Ryang, Dong Wook
Kim, Hyeoung Joon
Acquired Hemophilia Successfully Treated With Oral Immunosuppressive Therapy
title Acquired Hemophilia Successfully Treated With Oral Immunosuppressive Therapy
title_full Acquired Hemophilia Successfully Treated With Oral Immunosuppressive Therapy
title_fullStr Acquired Hemophilia Successfully Treated With Oral Immunosuppressive Therapy
title_full_unstemmed Acquired Hemophilia Successfully Treated With Oral Immunosuppressive Therapy
title_short Acquired Hemophilia Successfully Treated With Oral Immunosuppressive Therapy
title_sort acquired hemophilia successfully treated with oral immunosuppressive therapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531764/
https://www.ncbi.nlm.nih.gov/pubmed/10992727
http://dx.doi.org/10.3904/kjim.2000.15.2.135
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