Combined 3D-QSAR modeling and molecular docking study on multi-acting quinazoline derivatives as HER2 kinase inhibitors

A series of new quinazoline derivatives has been recently reported as potent multi-acting histone deacetylase (HDAC), epidermal growth factor receptor (EGFR), and human epidermal growth factor receptor 2 (HER2) inhibitors. HER2 is one of the major targets for the treatment of breast cancer and other...

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Detalles Bibliográficos
Autores principales: Mirzaie, Sako, Monajjemi, Majid, Hakhamaneshi, Mohammad Saeed, Fathi, Fardin, Jamalan, Mostafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531791/
https://www.ncbi.nlm.nih.gov/pubmed/26417222

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