Increased ectodomain shedding of cell adhesion molecule 1 as a cause of type II alveolar epithelial cell apoptosis in patients with idiopathic interstitial pneumonia

BACKGROUND: Lung alveolar epithelial cell (AEC) apoptosis has attracted attention as an early pathogenic event in the development of idiopathic interstitial pneumonia (IIP); however, the causative mechanism remains unclear. Cell adhesion molecule 1 (CADM1) is an AEC adhesion molecule in the immunogl...

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Detalles Bibliográficos
Autores principales: Yoneshige, Azusa, Hagiyama, Man, Inoue, Takao, Mimae, Takahiro, Kato, Takashi, Okada, Morihito, Enoki, Eisuke, Ito, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531801/
https://www.ncbi.nlm.nih.gov/pubmed/26231557
http://dx.doi.org/10.1186/s12931-015-0255-x

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