Quantitative detection of rare interphase chromosome breaks and translocations by high-throughput imaging

We report a method for the sensitive detection of rare chromosome breaks and translocations in interphase cells. HiBA-FISH (High-throughput break-apart FISH) combines high-throughput imaging with the measurement of the spatial separation of FISH probes flanking target genome regions of interest. As...

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Detalles Bibliográficos
Autores principales: Burman, Bharat, Misteli, Tom, Pegoraro, Gianluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531802/
https://www.ncbi.nlm.nih.gov/pubmed/26313373
http://dx.doi.org/10.1186/s13059-015-0718-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531802/
https://www.ncbi.nlm.nih.gov/pubmed/26313373
http://dx.doi.org/10.1186/s13059-015-0718-x

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