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Quantitative detection of rare interphase chromosome breaks and translocations by high-throughput imaging
We report a method for the sensitive detection of rare chromosome breaks and translocations in interphase cells. HiBA-FISH (High-throughput break-apart FISH) combines high-throughput imaging with the measurement of the spatial separation of FISH probes flanking target genome regions of interest. As...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531802/ https://www.ncbi.nlm.nih.gov/pubmed/26313373 http://dx.doi.org/10.1186/s13059-015-0718-x |