Successful Treatment with Ganciclovir for Cytomegalovirus Duodenitis following Allogenic Bone Marrow Transplantation

Cytomegalovirus (CMV) disease is a major cause of morbidity and mortality in immunocompromised patients. CMV enteritis should be considered when nausea and vomiting continue 3 to 4 weeks after bone marrow transplantation (BMT). The treatment of CMV enteritis is not well established. We report a CMV...

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Detalles Bibliográficos
Autores principales: Ahn, Jin Hee, Lee, Je-Hwan, Lee, Kyoo-Hyung, Kim, Woo-Kun, Lee, Jung-Shin, Bahng, Hyeseung, Jung, Hwoon-Yong, Kim, Yang-Soo, Kim, Onja, Kim, Sang-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Internal Medicine 1999
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531909/
https://www.ncbi.nlm.nih.gov/pubmed/10063321
http://dx.doi.org/10.3904/kjim.1999.14.1.91
Descripción
Sumario:Cytomegalovirus (CMV) disease is a major cause of morbidity and mortality in immunocompromised patients. CMV enteritis should be considered when nausea and vomiting continue 3 to 4 weeks after bone marrow transplantation (BMT). The treatment of CMV enteritis is not well established. We report a CMV duodenitis patient following allogenic bone marrow transplantation. The patient had prolonged nausea and vomiting for 5 weeks after bone marrow transplantation and CMV duodenitis was diagnosed by the gastroduodenoscopic mucosal biopsy which showed cytomegalic cells. Ganciclovir treatment for 3 weeks resulted in the resolution of symptoms and promoted healing of the lesion. The patient was free of CMV infection until 288 days after allogenic BMT without maintenance ganciclovir treatment.

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