A Case of Marfan Syndrome with Acute Monoblastic Leukemia

We report on an 18-year-old man who had both acute monoblastic leukemia and Marfan syndrome. A diagnosis of Marfan syndrome was established by those characteristics of arachnodactyly, ectopia lentis, mitral valve prolapse, and mitral regurgitation. Findings on bone marrow examination of the patient...

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Detalles Bibliográficos
Autores principales: Lee, Je Jung, Kim, Hyeoung Joon, Chung, Ik Joo, Jeong, Myung Ho, Kook, Hoon, Seo, Jea Sung, Kim, Nam Jin, Park, Moo Rim, Choi, Kyeoung Sang, Hwang, Tai Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Internal Medicine 1998
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531946/
https://www.ncbi.nlm.nih.gov/pubmed/9735672
http://dx.doi.org/10.3904/kjim.1998.13.2.140
Descripción
Sumario:We report on an 18-year-old man who had both acute monoblastic leukemia and Marfan syndrome. A diagnosis of Marfan syndrome was established by those characteristics of arachnodactyly, ectopia lentis, mitral valve prolapse, and mitral regurgitation. Findings on bone marrow examination of the patient showed that most of nucleated cells were monoblasts and immunophenotype of those cells showed CD13+, CD33+, CD56+, and HLA-DH+. To our knowledge, this is the second report of leukemia in Marfan syndrome in the world.

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