A Case of Idiopathic Thyrotropin (TSH) Deficiency

The first case of idiopathic thyrotropin (TSH) deficiency in an old woman with thyroid functioning adenoma was reported. She got subtotal thyroidectomy before about four years of her admission to our hospital because of fatigability, puffy face and leg edema. At that time, she had low TSH and free T...

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Detalles Bibliográficos
Autores principales: Ichida, Tatsuya, Kajita, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Internal Medicine 1997
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531965/
https://www.ncbi.nlm.nih.gov/pubmed/9159047
http://dx.doi.org/10.3904/kjim.1997.12.1.96
Descripción
Sumario:The first case of idiopathic thyrotropin (TSH) deficiency in an old woman with thyroid functioning adenoma was reported. She got subtotal thyroidectomy before about four years of her admission to our hospital because of fatigability, puffy face and leg edema. At that time, she had low TSH and free T(4) levels despite replacement therapy with desiccated thyroid. No response of only serum TSH after adminstration of combined stimulant containing TRH and repeated TRH suggested the failure of TSH secretion. CT MRI did not show any abnormality. These results indicated that her hypothyroidism was due to acquired idiopathic TSH deficiency.

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