Acute Lung Injury after Phosgene Inhalation

Phosgene (COCl(2)) is a colorless oxidant gas which is heavier than air and the lethal exposure dose (LC(50)) in humans is 500 ppm/min. This gas was originally manufactured as an agent for chemical warfare during World War I and there had been a great deal of studies on phosgene poisoning during the...

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Autores principales: Lim, Sung-Chul, Yang, Ju-Yeoul, Jang, An-Soo, Park, Yong-Uk, Kim, Young-Chul, Choi, In-Seon, Park, Kyung-Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Internal Medicine 1996
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532002/
https://www.ncbi.nlm.nih.gov/pubmed/8882481
http://dx.doi.org/10.3904/kjim.1996.11.1.87
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author Lim, Sung-Chul
Yang, Ju-Yeoul
Jang, An-Soo
Park, Yong-Uk
Kim, Young-Chul
Choi, In-Seon
Park, Kyung-Ok
author_facet Lim, Sung-Chul
Yang, Ju-Yeoul
Jang, An-Soo
Park, Yong-Uk
Kim, Young-Chul
Choi, In-Seon
Park, Kyung-Ok
author_sort Lim, Sung-Chul
collection PubMed
description Phosgene (COCl(2)) is a colorless oxidant gas which is heavier than air and the lethal exposure dose (LC(50)) in humans is 500 ppm/min. This gas was originally manufactured as an agent for chemical warfare during World War I and there had been a great deal of studies on phosgene poisoning during the early years of industrial use. It is still widely used in the synthesis of chemicals and plastics. In the modern era, however, phosgene poisoning is relatively uncommon except in accidental exposures. In Korea, there has been no report about lung injury from phosgene inhalation. We present a clinical experience with six patients accidentally exposed to phosgene.
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spelling pubmed-45320022015-10-02 Acute Lung Injury after Phosgene Inhalation Lim, Sung-Chul Yang, Ju-Yeoul Jang, An-Soo Park, Yong-Uk Kim, Young-Chul Choi, In-Seon Park, Kyung-Ok Korean J Intern Med Case Report Phosgene (COCl(2)) is a colorless oxidant gas which is heavier than air and the lethal exposure dose (LC(50)) in humans is 500 ppm/min. This gas was originally manufactured as an agent for chemical warfare during World War I and there had been a great deal of studies on phosgene poisoning during the early years of industrial use. It is still widely used in the synthesis of chemicals and plastics. In the modern era, however, phosgene poisoning is relatively uncommon except in accidental exposures. In Korea, there has been no report about lung injury from phosgene inhalation. We present a clinical experience with six patients accidentally exposed to phosgene. Korean Association of Internal Medicine 1996-01 /pmc/articles/PMC4532002/ /pubmed/8882481 http://dx.doi.org/10.3904/kjim.1996.11.1.87 Text en Copyright © 1996 The Korean Association of Internal Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Lim, Sung-Chul
Yang, Ju-Yeoul
Jang, An-Soo
Park, Yong-Uk
Kim, Young-Chul
Choi, In-Seon
Park, Kyung-Ok
Acute Lung Injury after Phosgene Inhalation
title Acute Lung Injury after Phosgene Inhalation
title_full Acute Lung Injury after Phosgene Inhalation
title_fullStr Acute Lung Injury after Phosgene Inhalation
title_full_unstemmed Acute Lung Injury after Phosgene Inhalation
title_short Acute Lung Injury after Phosgene Inhalation
title_sort acute lung injury after phosgene inhalation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532002/
https://www.ncbi.nlm.nih.gov/pubmed/8882481
http://dx.doi.org/10.3904/kjim.1996.11.1.87
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