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A Case of Amiodarone-Associated Pulmonary Toxicity

Amiodarone is an iodinated benzofuran derivative that represents a new and extremely effective therapy for certain life-threatening refractory cardiac arrgythmia. There are numerous side effects associated with amiodarone therapy, including corneal microdeposits. Skin reactions and others. Pulmonary...

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Detalles Bibliográficos
Autores principales: Kwon, Kang Ho, Jeong, Seong Whan, Uh, Sootaek, Kim, Yong Hoon, Jin, So Young, Park, Jae Sung, Kang, Chang Hee, Park, Choon Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Internal Medicine 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532041/
https://www.ncbi.nlm.nih.gov/pubmed/7495776
http://dx.doi.org/10.3904/kjim.1995.10.2.155
Descripción
Sumario:Amiodarone is an iodinated benzofuran derivative that represents a new and extremely effective therapy for certain life-threatening refractory cardiac arrgythmia. There are numerous side effects associated with amiodarone therapy, including corneal microdeposits. Skin reactions and others. Pulmonary toxicity, however, represents the most serious adverse reaction limiting the clinical efficacy of this antidysrhythmic drug, Recently, we experienced a case of amiodarone-induced pulmonary toxicity confirmed by open lung biopsy with light-and electron-microscopy. So, we report a case of amiodarone-induced pulmonary toxicity with a literature review.