Deconvoluting heme biosynthesis to target blood-stage malaria parasites

Heme metabolism is central to blood-stage infection by the malaria parasite Plasmodium falciparum. Parasites retain a heme biosynthesis pathway but do not require its activity during infection of heme-rich erythrocytes, where they can scavenge host heme to meet metabolic needs. Nevertheless, heme bi...

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Detalles Bibliográficos
Autores principales: Sigala, Paul A, Crowley, Jan R, Henderson, Jeffrey P, Goldberg, Daniel E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532139/
https://www.ncbi.nlm.nih.gov/pubmed/26173178
http://dx.doi.org/10.7554/eLife.09143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532139/
https://www.ncbi.nlm.nih.gov/pubmed/26173178
http://dx.doi.org/10.7554/eLife.09143

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