Cargando…

TLR7 and TLR8 expression increases tumor cell proliferation and promotes chemoresistance in human pancreatic cancer

Chronic inflammation as an important epigenetic and environmental factor for putative tumorigenesis and tumor progression may be associated with specific activation of Toll-like receptors (TLR). Recently, carcinogenesis has been suggested to be dependent on TLR7 signaling. In the present study, we d...

Descripción completa

Detalles Bibliográficos
Autores principales:	GRIMMIG, TANJA, MATTHES, NIELS, HOELAND, KATHARINA, TRIPATHI, SUDIPTA, CHANDRAKER, ANIL, GRIMM, MARTIN, MOENCH, ROMANA, MOLL, EVA-MARIA, FRIESS, HELMUT, TSAUR, IGOR, BLAHETA, ROMAN A., GERMER, CRISTOPH T., WAAGA-GASSER, ANA MARIA, GASSER, MARTIN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532221/ https://www.ncbi.nlm.nih.gov/pubmed/26134824 http://dx.doi.org/10.3892/ijo.2015.3069

Ejemplares similares

Exclusive inhibition of PI3K/Akt/mTOR signaling is not sufficient to prevent PDGF-mediated effects on glycolysis and proliferation in colorectal cancer
por: Moench, Romana, et al.
Publicado: (2016)

Toll Like Receptor 2, 4, and 9 Signaling Promotes Autoregulative Tumor Cell Growth and VEGF/PDGF Expression in Human Pancreatic Cancer
por: Grimmig, Tanja, et al.
Publicado: (2016)

Upregulated Heat Shock Proteins After Hyperthermic Chemotherapy Point to Induced Cell Survival Mechanisms in Affected Tumor Cells From Peritoneal Carcinomatosis
por: Grimmig, Tanja, et al.
Publicado: (2017)

Expression of Foxp3 in Colorectal Cancer but Not in Treg Cells Correlates with Disease Progression in Patients with Colorectal Cancer
por: Kim, Mia, et al.
Publicado: (2013)

The role of FOXP3 in disease progression in colorectal cancer patients
por: Grimmig, Tanja, et al.
Publicado: (2013)

Clinical Significance of Disseminated Pluripotent Tumor Cell Signature Expression in the Bone Marrow from Patients with Colorectal Cancer
por: Gasser, Martin, et al.
Publicado: (2017)

Adenosinergic Pathway and Linked Suppression: Two Critical Suppressive Mechanisms of Human Donor Antigen Specific Regulatory T Cell Lines Expanded Post Transplant
por: Tripathi, Sudipta, et al.
Publicado: (2022)

Expression of Tumor-mediated CD137 ligand in human colon cancer indicates dual signaling effects
por: Grimmig, Tanja, et al.
Publicado: (2019)

Platelet-derived growth factor (PDGF) cross-signaling via non-corresponding receptors indicates bypassed signaling in colorectal cancer
por: Moench, Romana, et al.
Publicado: (2022)

CCL2 Chemokine as a Potential Biomarker for Prostate Cancer: A Pilot Study
por: Tsaur, Igor, et al.
Publicado: (2015)

Evaluation of immunological escape mechanisms in a mouse model of colorectal liver metastases
por: Grimm, Martin, et al.
Publicado: (2010)

Resistance to the mTOR-inhibitor RAD001 elevates integrin α2- and β1-triggered motility, migration and invasion of prostate cancer cells
por: Tsaur, I, et al.
Publicado: (2012)

Molecular targeting of prostate cancer cells by a triple drug combination down-regulates integrin driven adhesion processes, delays cell cycle progression and interferes with the cdk-cyclin axis
por: Wedel, Steffen, et al.
Publicado: (2011)

Tumor Necrosis Factor-α is Associated with Positive Lymph Node Status in Patients with Recurrence of Colorectal Cancer – Indications for Anti-TNF-α Agents in Cancer Treatment
por: Grimm, M., et al.
Publicado: (2010)

CIP2A Influences Survival in Colon Cancer and Is Critical for Maintaining Myc Expression
por: Wiegering, Armin, et al.
Publicado: (2013)

The intraportal injection model: A practical animal model for hepatic metastases and tumor cell dissemination in human colon cancer
por: Thalheimer, Andreas, et al.
Publicado: (2009)

Protein phosphatases in TLR signaling
por: Seumen, Clovis H. T., et al.
Publicado: (2021)

PDE4D targeting enhances anti-tumor effects of sorafenib in clear cell renal cell carcinoma and attenuates MAPK/ERK signaling in a CRAF-dependent manner
por: Cao, Minghua, et al.
Publicado: (2022)

KMP01D Demonstrates Beneficial Anti-inflammatory Effects on Immune Cells: An ex vivo Preclinical Study of Patients With Colorectal Cancer
por: Gasser, Martin, et al.
Publicado: (2020)

Contribution of FPR and TLR9 to hypoxia-induced chemoresistance of ovarian cancer cells
por: Cai, Yongqing, et al.
Publicado: (2018)

Study of TLR3, TLR4 and TLR9 in breast carcinomas and their association with metastasis
por: González-Reyes, Salomé, et al.
Publicado: (2010)

Expression of TLR2, TLR4, and TLR9 in dermatomyositis and polymyositis
por: Kim, Geun-Tae, et al.
Publicado: (2009)

The Role of TLR2, TLR4, and TLR9 in the Pathogenesis of Atherosclerosis
por: Roshan, Mohsin H. K., et al.
Publicado: (2016)

The Effects of Oral and Enteric Campylobacter concisus Strains on Expression of TLR4, MD-2, TLR2, TLR5 and COX-2 in HT-29 Cells
por: Ismail, Yazan, et al.
Publicado: (2013)

TLR4 and TLR9 Expression in Different Phenotypes of Rhinitis
por: Lauriello, Maria, et al.
Publicado: (2012)

Association of Genetic Polymorphisms in TLR3, TLR4, TLR7, and TLR8 with the Clinical Forms of Dengue in Patients from Veracruz, Mexico
por: Posadas-Mondragón, Araceli, et al.
Publicado: (2020)

TLR4 signaling induced by lipopolysacharide or paclitaxel regulates tumor survival and chemoresistance in ovarian cancer
por: Szajnik, Marta, et al.
Publicado: (2009)

A prospective study on histone γ-H2AX and 53BP1 foci expression in rectal carcinoma patients: correlation with radiation therapy-induced outcome
por: Djuzenova, Cholpon S., et al.
Publicado: (2015)

Microglial activation by microbial neuraminidase through TLR2 and TLR4 receptors
por: Fernández-Arjona, María del Mar, et al.
Publicado: (2019)

The molecular basis for recognition of bacterial ligands at equine TLR2, TLR1 and TLR6
por: Irvine, Katherine Lucy, et al.
Publicado: (2013)

TLR2 and TLR4 in Ischemia Reperfusion Injury
por: Arslan, F., et al.
Publicado: (2010)

TLR4 and SARM1 modulate survival and chemoresistance in an HPV-positive cervical cancer cell line
por: Morale, Mirian Galliote, et al.
Publicado: (2022)

TLR-9, but not TLR-2, TLR-3 and TLR-4, is upregulated on peripheral blood mononuclear cells of patients with active systemic lupus erythematosus
por: Papadimitraki, ED, et al.
Publicado: (2005)

Aberrant Expression of TLR2, TLR7, TLR9, Splicing Variants of TLR4 and MYD88 in Chronic Lymphocytic Leukemia Patients
por: Skorka, Katarzyna, et al.
Publicado: (2021)

Role of TLR1, TLR2 and TLR6 in the modulation of intestinal inflammation and Candida albicans elimination
por: Choteau, Laura, et al.
Publicado: (2017)

Variation in the TLR10/TLR1/TLR6 Locus is the Major Genetic Determinant of Inter-Individual Difference in TLR1/2-Mediated Responses
por: Mikacenic, Carmen, et al.
Publicado: (2012)

Expression of TLR2, TLR3, TLR4, and TLR7 on pulmonary lymphocytes of Schistosoma japonicum-infected C57BL/6 mice
por: Chen, Dianhui, et al.
Publicado: (2019)

TLR choreography
por: Maxmen, Amy
Publicado: (2009)

Mimicking Metastases Including Tumor Stroma: A New Technique to Generate a Three-Dimensional Colorectal Cancer Model Based on a Biological Decellularized Intestinal Scaffold
por: Nietzer, Sarah, et al.
Publicado: (2016)

Eicosanoids in the Innate Immune Response: TLR and Non-TLR Routes
por: Alvarez, Yolanda, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_qcrdk11ce9t3t54c4ur16i5044