Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic mice

BACKGROUND: Enhanced supraspinal glutamate levels following nerve injury are associated with pathophysiological mechanisms responsible for neuropathic pain. Chronic pain can interfere with specific brain areas involved in glutamate-dependent neuropsychological processes, such as cognition, memory, a...

Descripción completa

Detalles Bibliográficos
Autores principales: Guida, F., Luongo, L., Marmo, F., Romano, R., Iannotta, M., Napolitano, F., Belardo, C., Marabese, I, D’Aniello, A., De Gregorio, D., Rossi, F., Piscitelli, F., Lattanzi, R., de Bartolomeis, A., Usiello, A., Di Marzo, V., de Novellis, V., Maione, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532244/
https://www.ncbi.nlm.nih.gov/pubmed/26260027
http://dx.doi.org/10.1186/s13041-015-0139-5

Ejemplares similares

Ejemplares similares