E3 Ubiquitin Ligase NEDD4 Promotes Influenza Virus Infection by Decreasing Levels of the Antiviral Protein IFITM3

Interferon (IFN)-induced transmembrane protein 3 (IFITM3) is a cell-intrinsic factor that limits influenza virus infections. We previously showed that IFITM3 degradation is increased by its ubiquitination, though the ubiquitin ligase responsible for this modification remained elusive. Here, we demon...

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Detalles Bibliográficos
Autores principales: Chesarino, Nicholas M., McMichael, Temet M., Yount, Jacob S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532365/
https://www.ncbi.nlm.nih.gov/pubmed/26263374
http://dx.doi.org/10.1371/journal.ppat.1005095

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