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The A Allele at rs13419896 of EPAS1 Is Associated with Enhanced Expression and Poor Prognosis for Non-Small Cell Lung Cancer

Hypoxia-inducible factor-2α (HIF-2α, or EPAS1) is important for cancer progression, and is a putative biomarker for poor prognosis for non-small cell lung cancer (NSCLC). However, molecular mechanisms underlying the EPAS1 overexpression are not still fully understood. We explored a role of a single...

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Detalles Bibliográficos
Autores principales: Putra, Andika C., Eguchi, Hidetaka, Lee, Kian Leong, Yamane, Yuko, Gustine, Ewita, Isobe, Takeshi, Nishiyama, Masahiko, Hiyama, Keiko, Poellinger, Lorenz, Tanimoto, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532412/
https://www.ncbi.nlm.nih.gov/pubmed/26263511
http://dx.doi.org/10.1371/journal.pone.0134496