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Binding of Multiple Rap1 Proteins Stimulates Chromosome Breakage Induction during DNA Replication
Telomeres, the ends of linear eukaryotic chromosomes, have a specialized chromatin structure that provides a stable chromosomal terminus. In budding yeast Rap1 protein binds to telomeric TG repeat and negatively regulates telomere length. Here we show that binding of multiple Rap1 proteins stimulate...
Autores principales: | Goto, Greicy H., Zencir, Sevil, Hirano, Yukinori, Ogi, Hiroo, Ivessa, Andreas, Sugimoto, Katsunori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532487/ https://www.ncbi.nlm.nih.gov/pubmed/26263073 http://dx.doi.org/10.1371/journal.pgen.1005283 |
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