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A Multi-Breed Genome-Wide Association Analysis for Canine Hypothyroidism Identifies a Shared Major Risk Locus on CFA12

Hypothyroidism is a complex clinical condition found in both humans and dogs, thought to be caused by a combination of genetic and environmental factors. In this study we present a multi-breed analysis of predisposing genetic risk factors for hypothyroidism in dogs using three high-risk breeds—the G...

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Detalles Bibliográficos
Autores principales: Bianchi, Matteo, Dahlgren, Stina, Massey, Jonathan, Dietschi, Elisabeth, Kierczak, Marcin, Lund-Ziener, Martine, Sundberg, Katarina, Thoresen, Stein Istre, Kämpe, Olle, Andersson, Göran, Ollier, William E. R., Hedhammar, Åke, Leeb, Tosso, Lindblad-Toh, Kerstin, Kennedy, Lorna J., Lingaas, Frode, Rosengren Pielberg, Gerli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532498/
https://www.ncbi.nlm.nih.gov/pubmed/26261983
http://dx.doi.org/10.1371/journal.pone.0134720