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Deficiency of autophagy protein Map1-LC3b mediates IL-17-dependent lung pathology during respiratory viral infection via ER stress associated IL-1
While recent studies suggest that IL-1β production is modulated by macroautophagy or sensors of ER stress upon pro-inflammatory insult, autophagy and IL-1β production during viral infection has not been fully investigated. This was addressed using respiratory syncytial virus (RSV), which is associat...
Autores principales: | Reed, Michelle, Morris, Susan H., Owczarczyk, Anna B., Lukacs, Nicholas W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532659/ https://www.ncbi.nlm.nih.gov/pubmed/25669150 http://dx.doi.org/10.1038/mi.2015.3 |
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