Interplay of H2A deubiquitinase 2A-DUB/Mysm1 and the p19(ARF)/p53 axis in hematopoiesis, early T-cell development and tissue differentiation

Monoubiquitination of core histone 2A (H2A-K119u) has a critical role in gene regulation in hematopoietic differentiation and other developmental processes. To explore the interplay of histone H2A deubiquitinase Myb-like SWIRM and MPN domain containing1 (2A-DUB/Mysm1) with the p53 axis in the sequen...

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Detalles Bibliográficos
Autores principales: Gatzka, M, Tasdogan, A, Hainzl, A, Allies, G, Maity, P, Wilms, C, Wlaschek, M, Scharffetter-Kochanek, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532772/
https://www.ncbi.nlm.nih.gov/pubmed/25613381
http://dx.doi.org/10.1038/cdd.2014.231

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