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Synthesis and Characterization with Antineoplastic, Biochemical, Cytotoxic, and Antimicrobial Studies of Schiff Base Cu(II) Ion Complexes
Copper(II) complexes containing two Schiff base ligands derived from 2-hydroxybenzaldehyde with 2-aminophenol and 3-aminophenol have been synthesized and characterized by means of analytical, magnetic, and spectroscopic methods. Bacteria, fungus, Entamoeba histolytica, and antineoplastic activities...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532810/ https://www.ncbi.nlm.nih.gov/pubmed/26294901 http://dx.doi.org/10.1155/2015/923087 |
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author | Haque, M. M. Kudrat-E-Zahan, Md. Banu, Laila Arjuman Islam, Md. Shariful Islam, M. S. |
author_facet | Haque, M. M. Kudrat-E-Zahan, Md. Banu, Laila Arjuman Islam, Md. Shariful Islam, M. S. |
author_sort | Haque, M. M. |
collection | PubMed |
description | Copper(II) complexes containing two Schiff base ligands derived from 2-hydroxybenzaldehyde with 2-aminophenol and 3-aminophenol have been synthesized and characterized by means of analytical, magnetic, and spectroscopic methods. Bacteria, fungus, Entamoeba histolytica, and antineoplastic activities of the synthesized complexes have been determined by monitoring the parameters cell growth inhibition, survival time of tumour mice, time-body relation, causing of intraperitoneal cells and macrophages, alkaline phosphatase activity, hematological effect, and biopsy of tumour. |
format | Online Article Text |
id | pubmed-4532810 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-45328102015-08-20 Synthesis and Characterization with Antineoplastic, Biochemical, Cytotoxic, and Antimicrobial Studies of Schiff Base Cu(II) Ion Complexes Haque, M. M. Kudrat-E-Zahan, Md. Banu, Laila Arjuman Islam, Md. Shariful Islam, M. S. Bioinorg Chem Appl Research Article Copper(II) complexes containing two Schiff base ligands derived from 2-hydroxybenzaldehyde with 2-aminophenol and 3-aminophenol have been synthesized and characterized by means of analytical, magnetic, and spectroscopic methods. Bacteria, fungus, Entamoeba histolytica, and antineoplastic activities of the synthesized complexes have been determined by monitoring the parameters cell growth inhibition, survival time of tumour mice, time-body relation, causing of intraperitoneal cells and macrophages, alkaline phosphatase activity, hematological effect, and biopsy of tumour. Hindawi Publishing Corporation 2015 2015-07-29 /pmc/articles/PMC4532810/ /pubmed/26294901 http://dx.doi.org/10.1155/2015/923087 Text en Copyright © 2015 M. M. Haque et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Haque, M. M. Kudrat-E-Zahan, Md. Banu, Laila Arjuman Islam, Md. Shariful Islam, M. S. Synthesis and Characterization with Antineoplastic, Biochemical, Cytotoxic, and Antimicrobial Studies of Schiff Base Cu(II) Ion Complexes |
title | Synthesis and Characterization with Antineoplastic, Biochemical, Cytotoxic, and Antimicrobial Studies of Schiff Base Cu(II) Ion Complexes |
title_full | Synthesis and Characterization with Antineoplastic, Biochemical, Cytotoxic, and Antimicrobial Studies of Schiff Base Cu(II) Ion Complexes |
title_fullStr | Synthesis and Characterization with Antineoplastic, Biochemical, Cytotoxic, and Antimicrobial Studies of Schiff Base Cu(II) Ion Complexes |
title_full_unstemmed | Synthesis and Characterization with Antineoplastic, Biochemical, Cytotoxic, and Antimicrobial Studies of Schiff Base Cu(II) Ion Complexes |
title_short | Synthesis and Characterization with Antineoplastic, Biochemical, Cytotoxic, and Antimicrobial Studies of Schiff Base Cu(II) Ion Complexes |
title_sort | synthesis and characterization with antineoplastic, biochemical, cytotoxic, and antimicrobial studies of schiff base cu(ii) ion complexes |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532810/ https://www.ncbi.nlm.nih.gov/pubmed/26294901 http://dx.doi.org/10.1155/2015/923087 |
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