Application and Progress of Combined Mesenchymal Stem Cell Transplantation in the Treatment of Ischemic Cardiomyopathy

Treatment of ischemic cardiomyopathy caused by myocardial infarction (MI) using mesenchymal stem cell (MSC) transplantation is a widely researched field, with promising clinical application. However, the low survival rate of transplanted cells has a severe impact on treatment outcome. Currently, res...

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Detalles Bibliográficos
Autores principales: Hua, Ping, Liu, Jian-Yang, Tao, Jun, Yang, Song-Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532814/
https://www.ncbi.nlm.nih.gov/pubmed/26295041
http://dx.doi.org/10.1155/2015/568502
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author Hua, Ping
Liu, Jian-Yang
Tao, Jun
Yang, Song-Ran
author_facet Hua, Ping
Liu, Jian-Yang
Tao, Jun
Yang, Song-Ran
author_sort Hua, Ping
collection PubMed
description Treatment of ischemic cardiomyopathy caused by myocardial infarction (MI) using mesenchymal stem cell (MSC) transplantation is a widely researched field, with promising clinical application. However, the low survival rate of transplanted cells has a severe impact on treatment outcome. Currently, research is focused on investigating the strategy of combining genetic engineering, tissue engineering materials, and drug/hypoxia preconditioning to improve ischemic cardiomyopathy treatment outcome using MSC transplantation treatment (MSCTT). This review discusses the application and progress of these techniques.
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spelling pubmed-45328142015-08-20 Application and Progress of Combined Mesenchymal Stem Cell Transplantation in the Treatment of Ischemic Cardiomyopathy Hua, Ping Liu, Jian-Yang Tao, Jun Yang, Song-Ran Biomed Res Int Review Article Treatment of ischemic cardiomyopathy caused by myocardial infarction (MI) using mesenchymal stem cell (MSC) transplantation is a widely researched field, with promising clinical application. However, the low survival rate of transplanted cells has a severe impact on treatment outcome. Currently, research is focused on investigating the strategy of combining genetic engineering, tissue engineering materials, and drug/hypoxia preconditioning to improve ischemic cardiomyopathy treatment outcome using MSC transplantation treatment (MSCTT). This review discusses the application and progress of these techniques. Hindawi Publishing Corporation 2015 2015-07-29 /pmc/articles/PMC4532814/ /pubmed/26295041 http://dx.doi.org/10.1155/2015/568502 Text en Copyright © 2015 Ping Hua et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Hua, Ping
Liu, Jian-Yang
Tao, Jun
Yang, Song-Ran
Application and Progress of Combined Mesenchymal Stem Cell Transplantation in the Treatment of Ischemic Cardiomyopathy
title Application and Progress of Combined Mesenchymal Stem Cell Transplantation in the Treatment of Ischemic Cardiomyopathy
title_full Application and Progress of Combined Mesenchymal Stem Cell Transplantation in the Treatment of Ischemic Cardiomyopathy
title_fullStr Application and Progress of Combined Mesenchymal Stem Cell Transplantation in the Treatment of Ischemic Cardiomyopathy
title_full_unstemmed Application and Progress of Combined Mesenchymal Stem Cell Transplantation in the Treatment of Ischemic Cardiomyopathy
title_short Application and Progress of Combined Mesenchymal Stem Cell Transplantation in the Treatment of Ischemic Cardiomyopathy
title_sort application and progress of combined mesenchymal stem cell transplantation in the treatment of ischemic cardiomyopathy
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532814/
https://www.ncbi.nlm.nih.gov/pubmed/26295041
http://dx.doi.org/10.1155/2015/568502
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