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Anatomy of protein disorder, flexibility and disease-related mutations

Integration of protein structural information with human genetic variation and pathogenic mutations is essential to understand molecular mechanisms associated with the effects of polymorphisms on protein interactions and cellular processes. We investigate occurrences of non-synonymous SNPs in ordere...

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Detalles Bibliográficos
Autores principales: Lu, Hui-Chun, Chung, Sun Sook, Fornili, Arianna, Fraternali, Franca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532925/
https://www.ncbi.nlm.nih.gov/pubmed/26322316
http://dx.doi.org/10.3389/fmolb.2015.00047

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