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A conserved histidine in switch-II of EF-G moderates release of inorganic phosphate

Elongation factor G (EF-G), a translational GTPase responsible for tRNA-mRNA translocation possesses a conserved histidine (H91 in Escherichia coli) at the apex of switch-II, which has been implicated in GTPase activation and GTP hydrolysis. While H91A, H91R and H91E mutants showed different degrees...

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Detalles Bibliográficos
Autores principales:	Kiran Koripella, Ravi, Holm, Mikael, Dourado, Daniel, Mandava, Chandra Sekhar, Flores, Samuel, Sanyal, Suparna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532990/ https://www.ncbi.nlm.nih.gov/pubmed/26264741 http://dx.doi.org/10.1038/srep12970

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