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Approaching rational epitope vaccine design for hepatitis C virus with meta-server and multivalent scaffolding

Development of a prophylactic vaccine against hepatitis C virus (HCV) has been hampered by the extraordinary viral diversity and the poor host immune response. Scaffolding, by grafting an epitope onto a heterologous protein scaffold, offers a possible solution to epitope vaccine design. In this stud...

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Detalles Bibliográficos
Autores principales:	He, Linling, Cheng, Yushao, Kong, Leopold, Azadnia, Parisa, Giang, Erick, Kim, Justin, Wood, Malcolm R., Wilson, Ian A., Law, Mansun, Zhu, Jiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533164/ https://www.ncbi.nlm.nih.gov/pubmed/26238798 http://dx.doi.org/10.1038/srep12501

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