Cargando…

ESEA: Discovering the Dysregulated Pathways based on Edge Set Enrichment Analysis

Pathway analyses are playing an increasingly important role in understanding biological mechanism, cellular function and disease states. Current pathway-identification methods generally focus on only the changes of gene expression levels; however, the biological relationships among genes are also th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Junwei, Shi, Xinrui, Zhang, Yunpeng, Xu, Yanjun, Jiang, Ying, Zhang, Chunlong, Feng, Li, Yang, Haixiu, Shang, Desi, Sun, Zeguo, Su, Fei, Li, Chunquan, Li, Xia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533315/ https://www.ncbi.nlm.nih.gov/pubmed/26267116 http://dx.doi.org/10.1038/srep13044

Ejemplares similares

The LncRNA Connectivity Map: Using LncRNA Signatures to Connect Small Molecules, LncRNAs, and Diseases
por: Yang, Haixiu, et al.
Publicado: (2017)

Subpathway-GMir: identifying miRNA-mediated metabolic subpathways by integrating condition-specific genes, microRNAs, and pathway topologies
por: Feng, Li, et al.
Publicado: (2015)

Global Prioritization of Disease Candidate Metabolites Based on a Multi-omics Composite Network
por: Yao, Qianlan, et al.
Publicado: (2015)

LncRNAs2Pathways: Identifying the pathways influenced by a set of lncRNAs of interest based on a global network propagation method
por: Han, Junwei, et al.
Publicado: (2017)

MPINet: Metabolite Pathway Identification via Coupling of Global Metabolite Network Structure and Metabolomic Profile
por: Li, Feng, et al.
Publicado: (2014)

Subpathway-GM: identification of metabolic subpathways via joint power of interesting genes and metabolites and their topologies within pathways
por: Li, Chunquan, et al.
Publicado: (2013)

Prioritizing Candidate Disease Metabolites Based on Global Functional Relationships between Metabolites in the Context of Metabolic Pathways
por: Shang, Desi, et al.
Publicado: (2014)

Subpathway-LNCE: Identify dysfunctional subpathways competitively regulated by lncRNAs through integrating lncRNA-mRNA expression profile and pathway topologies
por: Shi, Xinrui, et al.
Publicado: (2016)

MiRSEA: Discovering the pathways regulated by dysfunctional MicroRNAs
por: Han, Junwei, et al.
Publicado: (2016)

System level characterization of small molecule drugs and their affected long noncoding RNAs
por: Yang, Haixiu, et al.
Publicado: (2019)

BioM2MetDisease: a manually curated database for associations between microRNAs, metabolites, small molecules and metabolic diseases
por: Xu, Yanjun, et al.
Publicado: (2017)

Identification of Subtype Specific miRNA-mRNA Functional Regulatory Modules in Matched miRNA-mRNA Expression Data: Multiple Myeloma as a Case
por: Zhang, Yunpeng, et al.
Publicado: (2015)

LncSubpathway: a novel approach for identifying dysfunctional subpathways associated with risk lncRNAs by integrating lncRNA and mRNA expression profiles and pathway topologies
por: Xu, Yanjun, et al.
Publicado: (2017)

Characterizing the Network of Drugs and Their Affected Metabolic Subpathways
por: Li, Chunquan, et al.
Publicado: (2012)

Global view of a drug-sensitivity gene network
por: Yang, Haixiu, et al.
Publicado: (2017)

Identification of miRNA-Mediated Core Gene Module for Glioma Patient Prediction by Integrating High-Throughput miRNA, mRNA Expression and Pathway Structure
por: Zhang, Chunlong, et al.
Publicado: (2014)

ncDRMarker: a computational method for identifying non-coding RNA signatures of drug resistance based on heterogeneous network
por: Yang, Haixiu, et al.
Publicado: (2020)

Identifying subpathway signatures for individualized anticancer drug response by integrating multi-omics data
por: Xu, Yanjun, et al.
Publicado: (2019)

Inference of patient‐specific subpathway activities reveals a functional signature associated with the prognosis of patients with breast cancer
por: Han, Junwei, et al.
Publicado: (2018)

Cofunctional Subpathways Were Regulated by Transcription Factor with Common Motif, Common Family, or Common Tissue
por: Su, Fei, et al.
Publicado: (2015)

Development and Application of an ELISA Assay Using Excretion/Secretion Proteins from Epimastigote Forms of T. cruzi (ESEA Antigens) for the Diagnosis of Chagas Disease
por: Berrizbeitia, Mariolga, et al.
Publicado: (2012)

Comprehensive characterization of lncRNA-mRNA related ceRNA network across 12 major cancers
por: Zhang, Yunpeng, et al.
Publicado: (2016)

Integrating gene and lncRNA expression to infer subpathway activity for tumor analyses
por: Zhang, Chunlong, et al.
Publicado: (2017)

The Implications of Relationships between Human Diseases and Metabolic Subpathways
por: Li, Xia, et al.
Publicado: (2011)

Identifying individualized risk subpathways reveals pan-cancer molecular classification based on multi-omics data
por: Xu, Yanjun, et al.
Publicado: (2022)

Integrative Pathway Analysis of Genes and Metabolites Reveals Metabolism Abnormal Subpathway Regions and Modules in Esophageal Squamous Cell Carcinoma
por: Li, Chunquan, et al.
Publicado: (2017)

Discovering the forbidden Raman modes at the edges of layered materials
por: Guo, Yao, et al.
Publicado: (2018)

LncSEA: a platform for long non-coding RNA related sets and enrichment analysis
por: Chen, Jiaxin, et al.
Publicado: (2020)

Quantifying Risk Pathway Crosstalk Mediated by miRNA to Screen Precision drugs for Breast Cancer Patients
por: Xu, Yingqi, et al.
Publicado: (2019)

Discovering Pluto: exploration at the edge of the solar system
por: Cruikshank, Dale P, et al.
Publicado: (2018)

Topologically inferring pathway activity toward precise cancer classification via integrating genomic and metabolomic data: prostate cancer as a case
por: Liu, Wei, et al.
Publicado: (2015)

Discovering pathways by orienting edges in protein interaction networks
por: Gitter, Anthony, et al.
Publicado: (2011)

Discovering communities in complex networks by edge label propagation
por: Liu, Wei, et al.
Publicado: (2016)

Pseudo-time-reversal symmetry and topological edge states in two-dimensional acoustic crystals
por: Mei, Jun, et al.
Publicado: (2016)

Characterizing heterogeneity of non‐small cell lung tumour microenvironment to identify signature prognostic genes
por: Mi, Kai, et al.
Publicado: (2020)

Discovering chromatin dysregulation induced by protein-coding perturbations at scale
por: Frenkel, Max, et al.
Publicado: (2023)

Time-ordered dysregulated ceRNA networks reveal disease progression and diagnostic biomarkers in ischemic and dilated cardiomyopathy
por: Bai, Ziyi, et al.
Publicado: (2021)

Untargeted Metabolomics Analysis of Esophageal Squamous Cell Carcinoma Discovers Dysregulated Metabolic Pathways and Potential Diagnostic Biomarkers
por: Zhu, Zi-Jia, et al.
Publicado: (2020)

Phosphoproteomic dysregulation in Huntington’s disease mice is rescued by environmental enrichment
por: Mees, Isaline, et al.
Publicado: (2022)

Dissecting dysfunctional crosstalk pathways regulated by miRNAs during glioma progression
por: Zhang, Yunpeng, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_vrlmsb0hbal09l8oqblrti3pvl