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Superficial Siderosis of the Central Nervous System Caused by Hemorrhagic Intraventricular Craniopharyngioma: Case Report and Literature Review

Superficial siderosis is a rare condition caused by hemosiderin deposits in the central nervous system (CNS) due to prolonged or recurrent low-grade bleeding into the cerebrospinal fluid (CSF). CNS tumor could be one of the sources of bleeding, both pre- and postoperatively. We report an extremely r...

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Autores principales: TOSAKA, Masahiko, SATO, Koji, AMANUMA, Makoto, HIGUCHI, Tetsuya, ARAI, Motohiro, AISHIMA, Kaoru, SHIMIZU, Tatsuya, HORIGUCHI, Keishi, SUGAWARA, Kenichi, YOSHIMOTO, Yuhei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Neurosurgical Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533391/
https://www.ncbi.nlm.nih.gov/pubmed/24670310
http://dx.doi.org/10.2176/nmc.cr.2012-0362
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author TOSAKA, Masahiko
SATO, Koji
AMANUMA, Makoto
HIGUCHI, Tetsuya
ARAI, Motohiro
AISHIMA, Kaoru
SHIMIZU, Tatsuya
HORIGUCHI, Keishi
SUGAWARA, Kenichi
YOSHIMOTO, Yuhei
author_facet TOSAKA, Masahiko
SATO, Koji
AMANUMA, Makoto
HIGUCHI, Tetsuya
ARAI, Motohiro
AISHIMA, Kaoru
SHIMIZU, Tatsuya
HORIGUCHI, Keishi
SUGAWARA, Kenichi
YOSHIMOTO, Yuhei
author_sort TOSAKA, Masahiko
collection PubMed
description Superficial siderosis is a rare condition caused by hemosiderin deposits in the central nervous system (CNS) due to prolonged or recurrent low-grade bleeding into the cerebrospinal fluid (CSF). CNS tumor could be one of the sources of bleeding, both pre- and postoperatively. We report an extremely rare case of superficial siderosis associated with purely third ventricle craniopharyngioma, and review previously reported cases of superficial siderosis associated with CNS tumor. A 69-year-old man presented with headache, unsteady gait, blurred vision, and progressive hearing loss. Brain magnetic resonance (MR) imaging with gadolinium revealed a well enhanced, intraventricular mass in the anterior part of the third ventricle. T(2)*-weighted gradient echo (GE) MR imaging revealed a hypointense rim around the brain particularly marked within the depth of the sulci. Superficial siderosis was diagnosed based on these findings. The tumor was diffusely hypointense on T(2)*-weighted GE imaging, indicating intratumoral hemorrhage. The lateral ventricles were dilated, suggesting hydrocephalus. [(18)F]fluorodeoxyglucose positron emission tomography revealed increased uptake in the tumor. The whole brain surface appeared dark ocher at surgery. Histological examination showed the hemorrhagic tumor was papillary craniopharyngioma. His hearing loss progressed after removal of the tumor. T(2)*-weighted GE MR imaging demonstrated not only superficial siderosis but also diffuse intratumoral hemorrhage in the tumor. Superficial siderosis and its related symptoms, including hearing loss, should be considered in patients with hemorrhagic tumor related to the CSF space. Purely third ventricle craniopharyngioma rarely has hemorrhagic character, which could cause superficial siderosis and progressive hearing loss.
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spelling pubmed-45333912015-11-05 Superficial Siderosis of the Central Nervous System Caused by Hemorrhagic Intraventricular Craniopharyngioma: Case Report and Literature Review TOSAKA, Masahiko SATO, Koji AMANUMA, Makoto HIGUCHI, Tetsuya ARAI, Motohiro AISHIMA, Kaoru SHIMIZU, Tatsuya HORIGUCHI, Keishi SUGAWARA, Kenichi YOSHIMOTO, Yuhei Neurol Med Chir (Tokyo) Case Report Superficial siderosis is a rare condition caused by hemosiderin deposits in the central nervous system (CNS) due to prolonged or recurrent low-grade bleeding into the cerebrospinal fluid (CSF). CNS tumor could be one of the sources of bleeding, both pre- and postoperatively. We report an extremely rare case of superficial siderosis associated with purely third ventricle craniopharyngioma, and review previously reported cases of superficial siderosis associated with CNS tumor. A 69-year-old man presented with headache, unsteady gait, blurred vision, and progressive hearing loss. Brain magnetic resonance (MR) imaging with gadolinium revealed a well enhanced, intraventricular mass in the anterior part of the third ventricle. T(2)*-weighted gradient echo (GE) MR imaging revealed a hypointense rim around the brain particularly marked within the depth of the sulci. Superficial siderosis was diagnosed based on these findings. The tumor was diffusely hypointense on T(2)*-weighted GE imaging, indicating intratumoral hemorrhage. The lateral ventricles were dilated, suggesting hydrocephalus. [(18)F]fluorodeoxyglucose positron emission tomography revealed increased uptake in the tumor. The whole brain surface appeared dark ocher at surgery. Histological examination showed the hemorrhagic tumor was papillary craniopharyngioma. His hearing loss progressed after removal of the tumor. T(2)*-weighted GE MR imaging demonstrated not only superficial siderosis but also diffuse intratumoral hemorrhage in the tumor. Superficial siderosis and its related symptoms, including hearing loss, should be considered in patients with hemorrhagic tumor related to the CSF space. Purely third ventricle craniopharyngioma rarely has hemorrhagic character, which could cause superficial siderosis and progressive hearing loss. The Japan Neurosurgical Society 2015-01 2014-03-27 /pmc/articles/PMC4533391/ /pubmed/24670310 http://dx.doi.org/10.2176/nmc.cr.2012-0362 Text en © 2015 The Japan Neurosurgical Society This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Case Report
TOSAKA, Masahiko
SATO, Koji
AMANUMA, Makoto
HIGUCHI, Tetsuya
ARAI, Motohiro
AISHIMA, Kaoru
SHIMIZU, Tatsuya
HORIGUCHI, Keishi
SUGAWARA, Kenichi
YOSHIMOTO, Yuhei
Superficial Siderosis of the Central Nervous System Caused by Hemorrhagic Intraventricular Craniopharyngioma: Case Report and Literature Review
title Superficial Siderosis of the Central Nervous System Caused by Hemorrhagic Intraventricular Craniopharyngioma: Case Report and Literature Review
title_full Superficial Siderosis of the Central Nervous System Caused by Hemorrhagic Intraventricular Craniopharyngioma: Case Report and Literature Review
title_fullStr Superficial Siderosis of the Central Nervous System Caused by Hemorrhagic Intraventricular Craniopharyngioma: Case Report and Literature Review
title_full_unstemmed Superficial Siderosis of the Central Nervous System Caused by Hemorrhagic Intraventricular Craniopharyngioma: Case Report and Literature Review
title_short Superficial Siderosis of the Central Nervous System Caused by Hemorrhagic Intraventricular Craniopharyngioma: Case Report and Literature Review
title_sort superficial siderosis of the central nervous system caused by hemorrhagic intraventricular craniopharyngioma: case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533391/
https://www.ncbi.nlm.nih.gov/pubmed/24670310
http://dx.doi.org/10.2176/nmc.cr.2012-0362
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