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Primary Spinal Neurocytoma Involving the Medulla Oblongata: Two Case Reports and a Literature Review

Central neurocytoma is a rare neuroectodermal tumor found in young adults. These tumors are generally located in the lateral or third ventricles. Extraventricular neurocytoma in the spinal cord is extremely rare. We report on two patients with primary spinal neurocytomas who presented with progressi...

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Autores principales: WU, Liang, DENG, Xiaofeng, YANG, Chenlong, ZHAO, Lei, YANG, Tao, XU, Yulun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Neurosurgical Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533432/
https://www.ncbi.nlm.nih.gov/pubmed/24257485
http://dx.doi.org/10.2176/nmc.cr2012-0345
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author WU, Liang
DENG, Xiaofeng
YANG, Chenlong
ZHAO, Lei
YANG, Tao
XU, Yulun
author_facet WU, Liang
DENG, Xiaofeng
YANG, Chenlong
ZHAO, Lei
YANG, Tao
XU, Yulun
author_sort WU, Liang
collection PubMed
description Central neurocytoma is a rare neuroectodermal tumor found in young adults. These tumors are generally located in the lateral or third ventricles. Extraventricular neurocytoma in the spinal cord is extremely rare. We report on two patients with primary spinal neurocytomas who presented with progressive numbness and weakness in the limbs. Both patients had intramedullary masses between the medulla and the upper thoracic levels. The clinical, radiological, surgical, and pathological features of this abnormality are discussed, and all 20 reported cases were reviewed. In conclusion, neurocytoma should be included in the differential diagnosis of a spinal intramedullary tumor, and subtotal resection is acceptable for a relatively favorable prognosis if gross total removal is unachievable. The efficacy of adjuvant radiochemotherapy to control tumor recurrence is unknown.
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spelling pubmed-45334322015-11-05 Primary Spinal Neurocytoma Involving the Medulla Oblongata: Two Case Reports and a Literature Review WU, Liang DENG, Xiaofeng YANG, Chenlong ZHAO, Lei YANG, Tao XU, Yulun Neurol Med Chir (Tokyo) Case Report Central neurocytoma is a rare neuroectodermal tumor found in young adults. These tumors are generally located in the lateral or third ventricles. Extraventricular neurocytoma in the spinal cord is extremely rare. We report on two patients with primary spinal neurocytomas who presented with progressive numbness and weakness in the limbs. Both patients had intramedullary masses between the medulla and the upper thoracic levels. The clinical, radiological, surgical, and pathological features of this abnormality are discussed, and all 20 reported cases were reviewed. In conclusion, neurocytoma should be included in the differential diagnosis of a spinal intramedullary tumor, and subtotal resection is acceptable for a relatively favorable prognosis if gross total removal is unachievable. The efficacy of adjuvant radiochemotherapy to control tumor recurrence is unknown. The Japan Neurosurgical Society 2014-05 2013-11-20 /pmc/articles/PMC4533432/ /pubmed/24257485 http://dx.doi.org/10.2176/nmc.cr2012-0345 Text en © 2014 The Japan Neurosurgical Society This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Case Report
WU, Liang
DENG, Xiaofeng
YANG, Chenlong
ZHAO, Lei
YANG, Tao
XU, Yulun
Primary Spinal Neurocytoma Involving the Medulla Oblongata: Two Case Reports and a Literature Review
title Primary Spinal Neurocytoma Involving the Medulla Oblongata: Two Case Reports and a Literature Review
title_full Primary Spinal Neurocytoma Involving the Medulla Oblongata: Two Case Reports and a Literature Review
title_fullStr Primary Spinal Neurocytoma Involving the Medulla Oblongata: Two Case Reports and a Literature Review
title_full_unstemmed Primary Spinal Neurocytoma Involving the Medulla Oblongata: Two Case Reports and a Literature Review
title_short Primary Spinal Neurocytoma Involving the Medulla Oblongata: Two Case Reports and a Literature Review
title_sort primary spinal neurocytoma involving the medulla oblongata: two case reports and a literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533432/
https://www.ncbi.nlm.nih.gov/pubmed/24257485
http://dx.doi.org/10.2176/nmc.cr2012-0345
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