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Primary Spinal Neurocytoma Involving the Medulla Oblongata: Two Case Reports and a Literature Review
Central neurocytoma is a rare neuroectodermal tumor found in young adults. These tumors are generally located in the lateral or third ventricles. Extraventricular neurocytoma in the spinal cord is extremely rare. We report on two patients with primary spinal neurocytomas who presented with progressi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japan Neurosurgical Society
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533432/ https://www.ncbi.nlm.nih.gov/pubmed/24257485 http://dx.doi.org/10.2176/nmc.cr2012-0345 |
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author | WU, Liang DENG, Xiaofeng YANG, Chenlong ZHAO, Lei YANG, Tao XU, Yulun |
author_facet | WU, Liang DENG, Xiaofeng YANG, Chenlong ZHAO, Lei YANG, Tao XU, Yulun |
author_sort | WU, Liang |
collection | PubMed |
description | Central neurocytoma is a rare neuroectodermal tumor found in young adults. These tumors are generally located in the lateral or third ventricles. Extraventricular neurocytoma in the spinal cord is extremely rare. We report on two patients with primary spinal neurocytomas who presented with progressive numbness and weakness in the limbs. Both patients had intramedullary masses between the medulla and the upper thoracic levels. The clinical, radiological, surgical, and pathological features of this abnormality are discussed, and all 20 reported cases were reviewed. In conclusion, neurocytoma should be included in the differential diagnosis of a spinal intramedullary tumor, and subtotal resection is acceptable for a relatively favorable prognosis if gross total removal is unachievable. The efficacy of adjuvant radiochemotherapy to control tumor recurrence is unknown. |
format | Online Article Text |
id | pubmed-4533432 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | The Japan Neurosurgical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-45334322015-11-05 Primary Spinal Neurocytoma Involving the Medulla Oblongata: Two Case Reports and a Literature Review WU, Liang DENG, Xiaofeng YANG, Chenlong ZHAO, Lei YANG, Tao XU, Yulun Neurol Med Chir (Tokyo) Case Report Central neurocytoma is a rare neuroectodermal tumor found in young adults. These tumors are generally located in the lateral or third ventricles. Extraventricular neurocytoma in the spinal cord is extremely rare. We report on two patients with primary spinal neurocytomas who presented with progressive numbness and weakness in the limbs. Both patients had intramedullary masses between the medulla and the upper thoracic levels. The clinical, radiological, surgical, and pathological features of this abnormality are discussed, and all 20 reported cases were reviewed. In conclusion, neurocytoma should be included in the differential diagnosis of a spinal intramedullary tumor, and subtotal resection is acceptable for a relatively favorable prognosis if gross total removal is unachievable. The efficacy of adjuvant radiochemotherapy to control tumor recurrence is unknown. The Japan Neurosurgical Society 2014-05 2013-11-20 /pmc/articles/PMC4533432/ /pubmed/24257485 http://dx.doi.org/10.2176/nmc.cr2012-0345 Text en © 2014 The Japan Neurosurgical Society This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/ |
spellingShingle | Case Report WU, Liang DENG, Xiaofeng YANG, Chenlong ZHAO, Lei YANG, Tao XU, Yulun Primary Spinal Neurocytoma Involving the Medulla Oblongata: Two Case Reports and a Literature Review |
title | Primary Spinal Neurocytoma Involving the Medulla Oblongata: Two Case Reports and a Literature Review |
title_full | Primary Spinal Neurocytoma Involving the Medulla Oblongata: Two Case Reports and a Literature Review |
title_fullStr | Primary Spinal Neurocytoma Involving the Medulla Oblongata: Two Case Reports and a Literature Review |
title_full_unstemmed | Primary Spinal Neurocytoma Involving the Medulla Oblongata: Two Case Reports and a Literature Review |
title_short | Primary Spinal Neurocytoma Involving the Medulla Oblongata: Two Case Reports and a Literature Review |
title_sort | primary spinal neurocytoma involving the medulla oblongata: two case reports and a literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533432/ https://www.ncbi.nlm.nih.gov/pubmed/24257485 http://dx.doi.org/10.2176/nmc.cr2012-0345 |
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