Therapeutic Plasma Exchange—A New Dawn in the Treatment of Pemphigus Vulgaris

Pemphigus vulgaris is an autoimmune disorder that involves intraepithelial blistering and sores of skin and mucous membrane. It generally correlates with the levels of circulating autoantibodies; their removal seems a reasonable therapeutic approach. Therapeutic plasma exchange is hypothesized to re...

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Autores principales: Kumar, Rajesh, Jindal, Aikaj, Kaur, Amarjit, Gupta, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
E-IJD Therapeutic Round
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533556/
https://www.ncbi.nlm.nih.gov/pubmed/26288426
http://dx.doi.org/10.4103/0019-5154.160509
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author Kumar, Rajesh
Jindal, Aikaj
Kaur, Amarjit
Gupta, Sonia
author_facet Kumar, Rajesh
Jindal, Aikaj
Kaur, Amarjit
Gupta, Sonia
author_sort Kumar, Rajesh
collection PubMed
description Pemphigus vulgaris is an autoimmune disorder that involves intraepithelial blistering and sores of skin and mucous membrane. It generally correlates with the levels of circulating autoantibodies; their removal seems a reasonable therapeutic approach. Therapeutic plasma exchange is hypothesized to remove pathogenic autoantibodies and has been used in refractory or severe cases. It may be considered for rapid control of severe or recalcitrant pemphigus vulgaris and should be combined with use of concomitant immuno-suppressive.
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spelling pubmed-45335562015-08-18 Therapeutic Plasma Exchange—A New Dawn in the Treatment of Pemphigus Vulgaris Kumar, Rajesh Jindal, Aikaj Kaur, Amarjit Gupta, Sonia Indian J Dermatol E-IJD Therapeutic Round Pemphigus vulgaris is an autoimmune disorder that involves intraepithelial blistering and sores of skin and mucous membrane. It generally correlates with the levels of circulating autoantibodies; their removal seems a reasonable therapeutic approach. Therapeutic plasma exchange is hypothesized to remove pathogenic autoantibodies and has been used in refractory or severe cases. It may be considered for rapid control of severe or recalcitrant pemphigus vulgaris and should be combined with use of concomitant immuno-suppressive. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4533556/ /pubmed/26288426 http://dx.doi.org/10.4103/0019-5154.160509 Text en Copyright: © Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle E-IJD Therapeutic Round
Kumar, Rajesh
Jindal, Aikaj
Kaur, Amarjit
Gupta, Sonia
Therapeutic Plasma Exchange—A New Dawn in the Treatment of Pemphigus Vulgaris
title Therapeutic Plasma Exchange—A New Dawn in the Treatment of Pemphigus Vulgaris
title_full Therapeutic Plasma Exchange—A New Dawn in the Treatment of Pemphigus Vulgaris
title_fullStr Therapeutic Plasma Exchange—A New Dawn in the Treatment of Pemphigus Vulgaris
title_full_unstemmed Therapeutic Plasma Exchange—A New Dawn in the Treatment of Pemphigus Vulgaris
title_short Therapeutic Plasma Exchange—A New Dawn in the Treatment of Pemphigus Vulgaris
title_sort therapeutic plasma exchange—a new dawn in the treatment of pemphigus vulgaris
topic E-IJD Therapeutic Round
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533556/
https://www.ncbi.nlm.nih.gov/pubmed/26288426
http://dx.doi.org/10.4103/0019-5154.160509
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