Tranexamic Acid-Induced Fixed Drug Eruption

A 33-year-old male showed multiple pigmented patches on his trunk and extremities after he took tranexamic acid for common cold. He stated that similar eruptions appeared when he was treated with tranexamic acid for influenza 10 months before. Patch test showed positive results at 48 h and 72 h by 1...

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Detalles Bibliográficos
Autores principales: Matsumura, Natsuko, Hanami, Yuka, Yamamoto, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
E-IJD Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533568/
https://www.ncbi.nlm.nih.gov/pubmed/26288438
http://dx.doi.org/10.4103/0019-5154.160524
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author Matsumura, Natsuko
Hanami, Yuka
Yamamoto, Toshiyuki
author_facet Matsumura, Natsuko
Hanami, Yuka
Yamamoto, Toshiyuki
author_sort Matsumura, Natsuko
collection PubMed
description A 33-year-old male showed multiple pigmented patches on his trunk and extremities after he took tranexamic acid for common cold. He stated that similar eruptions appeared when he was treated with tranexamic acid for influenza 10 months before. Patch test showed positive results at 48 h and 72 h by 1% and 10% tranexamic acid at the lesional skin only. To our knowledge, nine cases of fixed drug eruption induced by tranexamic acid have been reported in Japan. Tranexamic acid is a safe drug and frequently used because of its anti-fibrinolytic and anti-inflammatory effects, but caution of inducing fixed drug eruption should be necessary.
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spelling pubmed-45335682015-08-18 Tranexamic Acid-Induced Fixed Drug Eruption Matsumura, Natsuko Hanami, Yuka Yamamoto, Toshiyuki Indian J Dermatol E-IJD Case Report A 33-year-old male showed multiple pigmented patches on his trunk and extremities after he took tranexamic acid for common cold. He stated that similar eruptions appeared when he was treated with tranexamic acid for influenza 10 months before. Patch test showed positive results at 48 h and 72 h by 1% and 10% tranexamic acid at the lesional skin only. To our knowledge, nine cases of fixed drug eruption induced by tranexamic acid have been reported in Japan. Tranexamic acid is a safe drug and frequently used because of its anti-fibrinolytic and anti-inflammatory effects, but caution of inducing fixed drug eruption should be necessary. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4533568/ /pubmed/26288438 http://dx.doi.org/10.4103/0019-5154.160524 Text en Copyright: © Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle E-IJD Case Report
Matsumura, Natsuko
Hanami, Yuka
Yamamoto, Toshiyuki
Tranexamic Acid-Induced Fixed Drug Eruption
title Tranexamic Acid-Induced Fixed Drug Eruption
title_full Tranexamic Acid-Induced Fixed Drug Eruption
title_fullStr Tranexamic Acid-Induced Fixed Drug Eruption
title_full_unstemmed Tranexamic Acid-Induced Fixed Drug Eruption
title_short Tranexamic Acid-Induced Fixed Drug Eruption
title_sort tranexamic acid-induced fixed drug eruption
topic E-IJD Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533568/
https://www.ncbi.nlm.nih.gov/pubmed/26288438
http://dx.doi.org/10.4103/0019-5154.160524
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AT hanamiyuka tranexamicacidinducedfixeddrugeruption
AT yamamototoshiyuki tranexamicacidinducedfixeddrugeruption

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