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CDH1 and IL1-beta expression dictates FAK and MAPKK-dependent cross-talk between cancer cells and human mesenchymal stem cells
INTRODUCTION: Tumor microenvironment conferred by stromal (mesenchymal) stem cells (MSCs) plays a key role in tumor development, progression, and response to therapy. Defining the role of MSCs in tumorigenesis is crucial for their safe utilization in regenerative medicine. Herein, we conducted compr...
Autores principales: | Al-toub, Mashael, Vishnubalaji, Radhakrishnan, Hamam, Rimi, Kassem, Moustapha, Aldahmash, Abdullah, Alajez, Nehad M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533790/ https://www.ncbi.nlm.nih.gov/pubmed/26204886 http://dx.doi.org/10.1186/s13287-015-0123-0 |
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