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Cis-existence of H3K27me3 and H3K36me2 in mouse embryonic stem cells revealed by specific ions of isobaric modification chromatogram

INTRODUCTION: Histone H3 lysine 27 trimethylation (H3K27me3) and H3 lysine 36 trimethylation (H3K36me3) are important epigenetic modifications correlated with transcription repression and activation, respectively. These two opposing modifications rarely co-exist in the same H3 polypeptide. However,...

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Detalles Bibliográficos
Autores principales:	Mao, Hailei, Han, Gang, Xu, Longyong, Zhu, Duming, Lin, Hanqing, Cao, Xiongwen, Yu, Yi, Chen, Charlie Degui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533945/ https://www.ncbi.nlm.nih.gov/pubmed/26194893 http://dx.doi.org/10.1186/s13287-015-0131-0

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