Effect of IKZF1 deletions on signal transduction pathways in Philadelphia chromosome negative pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL)

BACKGROUND: IKZF1 deletions are an unfavorable prognostic factor in children with Philadelphia chromosome positive (Ph(+)) as well as negative (Ph(−)) acute lymphoblastic leukemia (ALL). Although IKZF1 deletions occur in 10–15% of Ph(−) ALL cases, effects of IKZF1 deletions on signaling pathways in...

Descripción completa

Detalles Bibliográficos
Autores principales: van der Sligte, Naomi E, Scherpen, Frank J G, ter Elst, Arja, Guryev, Victor, van Leeuwen, Frank N, de Bont, Eveline S J M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534008/
https://www.ncbi.nlm.nih.gov/pubmed/26269779
http://dx.doi.org/10.1186/s40164-015-0017-y

Ejemplares similares

Ejemplares similares