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The Mechanism by which 146-N-Glycan Affects the Active Site of Neuraminidase
One of the most conserved glycosylation sites of neuraminidase (NA) is 146-N-glycan. This site is adjacent to the 150-cavity of NA, which is found within the active site and thought to be a target for rational drug development against the antiviral resistance of influenza. Here, through a total of 2...
Autores principales: | Liu, Pi, Wang, Zhonghua, Zhang, Lijie, Li, Dongmei, Lin, Jianping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534095/ https://www.ncbi.nlm.nih.gov/pubmed/26267136 http://dx.doi.org/10.1371/journal.pone.0135487 |
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