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A Hamster Model of Diet-Induced Obesity for Preclinical Evaluation of Anti-Obesity, Anti-Diabetic and Lipid Modulating Agents
AIM: Unlike rats and mice, hamsters develop hypercholesterolemia, and hypertriglyceridemia when fed a cholesterol-rich diet. Because hyperlipidemia is a hallmark of human obesity, we aimed to develop and characterize a novel diet-induced obesity (DIO) and hypercholesterolemia Golden Syrian hamster m...
Autores principales: | Dalbøge, Louise S., Pedersen, Philip J., Hansen, Gitte, Fabricius, Katrine, Hansen, Henrik B., Jelsing, Jacob, Vrang, Niels |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534139/ https://www.ncbi.nlm.nih.gov/pubmed/26266945 http://dx.doi.org/10.1371/journal.pone.0135634 |
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