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Involvement of Rho-associated protein kinase (ROCK) and bone morphogenetic protein-binding endothelial cell precursor-derived regulator (BMPER) in high glucose-increased alkaline phosphatase expression and activity in human coronary artery smooth muscle cells

BACKGROUND: Vascular calcification is an independent risk factor for cardiovascular disease. Diabetes mellitus increases the incidence of vascular calcification; however, detailed molecular mechanisms of vascular calcification in diabetes mellitus remain unknown. We recently reported that bone morph...

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Detalles Bibliográficos
Autores principales: Terao, Yuya, Satomi-Kobayashi, Seimi, Hirata, Ken-ichi, Rikitake, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534147/
https://www.ncbi.nlm.nih.gov/pubmed/26264461
http://dx.doi.org/10.1186/s12933-015-0271-7