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Binding of the Lactococcal Drug Dependent Transcriptional Regulator LmrR to Its Ligands and Responsive Promoter Regions
The heterodimeric ABC transporter LmrCD from Lactococcus lactis is able to extrude several different toxic compounds from the cell, fulfilling a role in the intrinsic and induced drug resistance. The expression of the lmrCD genes is regulated by the multi-drug binding repressor LmrR, which also bind...
Autores principales: | van der Berg, Jan Pieter, Madoori, Pramod Kumar, Komarudin, Amalina Ghaisani, Thunnissen, Andy-Mark, Driessen, Arnold J. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534193/ https://www.ncbi.nlm.nih.gov/pubmed/26267906 http://dx.doi.org/10.1371/journal.pone.0135467 |
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