Cargando…
Assessments of Thioridazine as a Helper Compound to Dicloxacillin against Methicillin-Resistant Staphylococcus aureus: In Vivo Trials in a Mouse Peritonitis Model
INTRODUCTION: The rise in antimicrobial resistance is a major global concern and requires new treatment strategies. The use of helper compounds, such as thioridazine (TDZ), an antipsychotic drug, in combination with traditional antibiotics must be investigated. OBJECTIVES: The aim of this study was...
Autores principales: | Stenger, Michael, Hendel, Kristoffer, Bollen, Peter, Licht, Peter B., Kolmos, Hans Jørn, Klitgaard, Janne K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534400/ https://www.ncbi.nlm.nih.gov/pubmed/26267376 http://dx.doi.org/10.1371/journal.pone.0135571 |
Ejemplares similares
-
Systemic thioridazine in combination with dicloxacillin against early aortic graft infections caused by Staphylococcus aureus in a porcine model: In vivo results do not reproduce the in vitro synergistic activity
por: Stenger, Michael, et al.
Publicado: (2017) -
Molecular mechanisms of thioridazine resistance in Staphylococcus aureus
por: Wassmann, Claes Søndergaard, et al.
Publicado: (2018) -
Thioridazine Induces Major Changes in Global Gene Expression and Cell Wall Composition in Methicillin-Resistant Staphylococcus aureus USA300
por: Thorsing, Mette, et al.
Publicado: (2013) -
In vitro activity effects of combinations of cephalothin, dicloxacillin, imipenem, vancomycin and amikacin against methicillin-resistant Staphylococcus spp. strains
por: Miranda-Novales, Guadalupe, et al.
Publicado: (2006) -
Cannabidiol is an effective helper compound in combination with bacitracin to kill Gram-positive bacteria
por: Wassmann, Claes Søndergaard, et al.
Publicado: (2020)