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Ethanol Upregulates NMDA Receptor Subunit Gene Expression in Human Embryonic Stem Cell-Derived Cortical Neurons
Chronic alcohol consumption may result in sustained gene expression alterations in the brain, leading to alcohol abuse or dependence. Because of ethical concerns of using live human brain cells in research, this hypothesis cannot be tested directly in live human brains. In the present study, we used...
Autores principales: | Xiang, Yangfei, Kim, Kun-Yong, Gelernter, Joel, Park, In-Hyun, Zhang, Huiping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534442/ https://www.ncbi.nlm.nih.gov/pubmed/26266540 http://dx.doi.org/10.1371/journal.pone.0134907 |
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