Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report

Granulomatous amoebic encephalitis (GAE) due to Acanthamoeba is almost a uniformly fatal infection in immune-compromised hosts despite multidrug combination therapy. We report a case of GAE in a female who received a deceased donor kidney graft. She was treated with a combination of miltefosine, pen...

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Detalles Bibliográficos
Autores principales: Salameh, Ahmad, Bello, Nancy, Becker, Jennifer, Zangeneh, Tirdad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534522/
https://www.ncbi.nlm.nih.gov/pubmed/26280011
http://dx.doi.org/10.1093/ofid/ofv104
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author Salameh, Ahmad
Bello, Nancy
Becker, Jennifer
Zangeneh, Tirdad
author_facet Salameh, Ahmad
Bello, Nancy
Becker, Jennifer
Zangeneh, Tirdad
author_sort Salameh, Ahmad
collection PubMed
description Granulomatous amoebic encephalitis (GAE) due to Acanthamoeba is almost a uniformly fatal infection in immune-compromised hosts despite multidrug combination therapy. We report a case of GAE in a female who received a deceased donor kidney graft. She was treated with a combination of miltefosine, pentamidine, sulfadiazine, fluconazole, flucytosine, and azithromycin.
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spelling pubmed-45345222015-08-14 Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report Salameh, Ahmad Bello, Nancy Becker, Jennifer Zangeneh, Tirdad Open Forum Infect Dis Brief Reports Granulomatous amoebic encephalitis (GAE) due to Acanthamoeba is almost a uniformly fatal infection in immune-compromised hosts despite multidrug combination therapy. We report a case of GAE in a female who received a deceased donor kidney graft. She was treated with a combination of miltefosine, pentamidine, sulfadiazine, fluconazole, flucytosine, and azithromycin. Oxford University Press 2015-07-10 /pmc/articles/PMC4534522/ /pubmed/26280011 http://dx.doi.org/10.1093/ofid/ofv104 Text en © The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com.
spellingShingle Brief Reports
Salameh, Ahmad
Bello, Nancy
Becker, Jennifer
Zangeneh, Tirdad
Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report
title Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report
title_full Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report
title_fullStr Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report
title_full_unstemmed Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report
title_short Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report
title_sort fatal granulomatous amoebic encephalitis caused by acanthamoeba in a patient with kidney transplant: a case report
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534522/
https://www.ncbi.nlm.nih.gov/pubmed/26280011
http://dx.doi.org/10.1093/ofid/ofv104
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