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Ocular pseudoexfoliation syndrome and life span
BACKGROUND: To compare life span of persons with and without ocular pseudoexfoliation syndrome (PES). METHODS: The study is based on an epidemiological survey conducted in Sør-Trøndelag county, Norway, in 1985–86. All inhabitants over 64 years of age (2109 individuals) were invited. Mortality inform...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534680/ https://www.ncbi.nlm.nih.gov/pubmed/26288849 http://dx.doi.org/10.1016/j.ebiom.2015.05.024 |
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author | Slettedal, Jon Klokk Sandvik, Leiv Ringvold, Amund |
author_facet | Slettedal, Jon Klokk Sandvik, Leiv Ringvold, Amund |
author_sort | Slettedal, Jon Klokk |
collection | PubMed |
description | BACKGROUND: To compare life span of persons with and without ocular pseudoexfoliation syndrome (PES). METHODS: The study is based on an epidemiological survey conducted in Sør-Trøndelag county, Norway, in 1985–86. All inhabitants over 64 years of age (2109 individuals) were invited. Mortality information was obtained from The Norwegian Institute of Public Health in 2014, by which time 99% of the participants were deceased. RESULTS: When adjusting for age and gender, life span was not statistically different in persons with and without PES. Following the diagnosis of PES, patients' survival was up to, and beyond, 30 years. CONCLUSIONS: Our observations suggest that, despite all the systemic aberrations reported in persons with ocular PES, none or only marginal functional changes are caused in extraocular organs and tissues. The present study supports the notion that systemic PES is not a life-threatening condition. |
format | Online Article Text |
id | pubmed-4534680 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-45346802015-08-18 Ocular pseudoexfoliation syndrome and life span Slettedal, Jon Klokk Sandvik, Leiv Ringvold, Amund EBioMedicine Original Article BACKGROUND: To compare life span of persons with and without ocular pseudoexfoliation syndrome (PES). METHODS: The study is based on an epidemiological survey conducted in Sør-Trøndelag county, Norway, in 1985–86. All inhabitants over 64 years of age (2109 individuals) were invited. Mortality information was obtained from The Norwegian Institute of Public Health in 2014, by which time 99% of the participants were deceased. RESULTS: When adjusting for age and gender, life span was not statistically different in persons with and without PES. Following the diagnosis of PES, patients' survival was up to, and beyond, 30 years. CONCLUSIONS: Our observations suggest that, despite all the systemic aberrations reported in persons with ocular PES, none or only marginal functional changes are caused in extraocular organs and tissues. The present study supports the notion that systemic PES is not a life-threatening condition. Elsevier 2015-05-30 /pmc/articles/PMC4534680/ /pubmed/26288849 http://dx.doi.org/10.1016/j.ebiom.2015.05.024 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Article Slettedal, Jon Klokk Sandvik, Leiv Ringvold, Amund Ocular pseudoexfoliation syndrome and life span |
title | Ocular pseudoexfoliation syndrome and life span |
title_full | Ocular pseudoexfoliation syndrome and life span |
title_fullStr | Ocular pseudoexfoliation syndrome and life span |
title_full_unstemmed | Ocular pseudoexfoliation syndrome and life span |
title_short | Ocular pseudoexfoliation syndrome and life span |
title_sort | ocular pseudoexfoliation syndrome and life span |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534680/ https://www.ncbi.nlm.nih.gov/pubmed/26288849 http://dx.doi.org/10.1016/j.ebiom.2015.05.024 |
work_keys_str_mv | AT slettedaljonklokk ocularpseudoexfoliationsyndromeandlifespan AT sandvikleiv ocularpseudoexfoliationsyndromeandlifespan AT ringvoldamund ocularpseudoexfoliationsyndromeandlifespan |