TYK2 Promoter Variant and Diabetes Mellitus in the Japanese

BACKGROUND: Recently, natural mutation of Tyrosine kinase 2 (Tyk2) gene has been shown to determine susceptibility to murine virus-induced diabetes. In addition, a previous human genome-wide study suggested the type 1 diabetes (T1D) susceptibility region to be 19p13, where the human TYK2 gene is loc...

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Detalles Bibliográficos
Autores principales: Nagafuchi, Seiho, Kamada-Hibio, Yumi, Hirakawa, Kanako, Tsutsu, Nobutaka, Minami, Masae, Okada, Akira, Kai, Katsuya, Teshima, Miho, Moroishi, Arisa, Murakami, Yoshikazu, Umeno, Yoshikazu, Yokogawa, Yasushi, Kogawa, Kazuhiko, Izumi, Kenichi, Anzai, Keizo, Iwakiri, Ryuichi, Hamaguchi, Kazuyuki, Sasaki, Nobuhiro, Nohara, Sakae, Yoshida, Eiko, Harada, Mine, Akashi, Koichi, Yanase, Toshihiko, Ono, Junko, Okeda, Toshimitsu, Fujimoto, Ryoji, Ihara, Kenji, Hara, Toshiro, Kikuchi, Yohei, Iwase, Masanori, Kitazono, Takanari, Kojima, Fumiko, Kono, Suminori, Kurisaki, Hironori, Kondo, Shiori, Katsuta, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534683/
https://www.ncbi.nlm.nih.gov/pubmed/26288847
http://dx.doi.org/10.1016/j.ebiom.2015.05.004

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