Investigation of Efavirenz Discontinuation in Multi-ethnic Populations of HIV-positive Individuals by Genetic Analysis

BACKGROUND: Efavirenz (EFV) based antiretroviral therapy is expanding worldwide. However discontinuation of EFV containing regimens is common in some patients, particularly black patients, due most often to neuropsychiatric side effects. These adverse drug effects often result in premature drug disc...

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Detalles Bibliográficos
Autores principales: Cummins, Nathan W., Neuhaus, Jacqueline, Chu, Haitao, Neaton, James, Wyen, Christoph, Rockstroh, Jürgen K., Skiest, Daniel J., Boyd, Mark A., Khoo, Saye, Rotger, Margalida, Telenti, Amalio, Weinshilboum, Richard, Badley, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534686/
https://www.ncbi.nlm.nih.gov/pubmed/26288843
http://dx.doi.org/10.1016/j.ebiom.2015.05.012

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