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Loss of NDRG2 enhanced activation of the NF-κB pathway by PTEN and NIK phosphorylation for ATL and other cancer development

The activation of nuclear factor kappa B (NF-κB) signaling has a central role in the development of adult T-cell leukemia/lymphoma (ATL) and many other cancers. However, the activation mechanism of the NF-κB pathways remains poorly understood. Recently, we reported that N-myc downstream-regulated ge...

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Detalles Bibliográficos
Autores principales: Ichikawa, Tomonaga, Nakahata, Shingo, Fujii, Masahiro, Iha, Hidekatsu, Morishita, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534796/
https://www.ncbi.nlm.nih.gov/pubmed/26269411
http://dx.doi.org/10.1038/srep12841

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