Cargando…

RXFP1 is Targeted by Complement C1q Tumor Necrosis Factor-Related Factor 8 in Brain Cancer

The relaxin-like RXFP1 ligand–receptor system has important functions in tumor growth and tissue invasion. Recently, we have identified the secreted protein, CTRP8, a member of the C1q/tumor necrosis factor-related protein (CTRP) family, as a novel ligand of the relaxin receptor, RXFP1, with functio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thanasupawat, Thatchawan, Glogowska, Aleksandra, Burg, Maxwell, Wong, G. William, Hoang-Vu, Cuong, Hombach-Klonisch, Sabine, Klonisch, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534857/ https://www.ncbi.nlm.nih.gov/pubmed/26322020 http://dx.doi.org/10.3389/fendo.2015.00127

Ejemplares similares

Novel CTRP8‐RXFP1‐JAK3‐STAT3 axis promotes Cdc42‐dependent actin remodeling for enhanced filopodia formation and motility in human glioblastoma cells
por: Glogowska, Aleksandra, et al.
Publicado: (2021)

C1q/TNF‐related peptide 8 (CTRP8) promotes temozolomide resistance in human glioblastoma
por: Thanasupawat, Thatchawan, et al.
Publicado: (2018)

Mechanisms of Therapeutic Resistance in Cancer (Stem) Cells with Emphasis on Thyroid Cancer Cells
por: Hombach-Klonisch, Sabine, et al.
Publicado: (2014)

Nuclear High Mobility Group A2 (HMGA2) Interactome Revealed by Biotin Proximity Labeling
por: Gaudreau-Lapierre, Antoine, et al.
Publicado: (2023)

Dovitinib enhances temozolomide efficacy in glioblastoma cells
por: Thanasupawat, Thatchawan, et al.
Publicado: (2017)

Ubiquitin Proteasome Gene Signatures in Ependymoma Molecular Subtypes
por: Vriend, Jerry, et al.
Publicado: (2022)

Relaxin reduces xenograft tumour growth of human MDA-MB-231 breast cancer cells
por: Radestock, Yvonne, et al.
Publicado: (2008)

Corrigendum to “Epidermal Growth Factor Cytoplasmic Domain Affects ErbB Protein Degradation by the Lysosomal and Ubiquitin–Proteasome Pathway in Human Cancer Cells” [Neoplasia 14 (2012) 396–409]
por: Glogowska, Aleksandra, et al.
Publicado: (2017)

HMGA2 as a functional antagonist of PARP1 inhibitors in tumor cells
por: Hombach‐Klonisch, Sabine, et al.
Publicado: (2018)

C1q/TNF-Related Proteins 1, 6 and 8 Are Involved in Corneal Epithelial Wound Closure by Targeting Relaxin Receptor RXFP1 In Vitro
por: Nicolaus, Hagen Fabian, et al.
Publicado: (2023)

Slow Off-Rate Modified Aptamer (SOMAmer) Proteomic Analysis of Patient-Derived Malignant Glioma Identifies Distinct Cellular Proteomes
por: Thanasupawat, Thatchawan, et al.
Publicado: (2021)

In a Class of Their Own – RXFP1 and RXFP2 are Unique Members of the LGR Family
por: Petrie, Emma J., et al.
Publicado: (2015)

DUBing Primary Tumors of the Central Nervous System: Regulatory Roles of Deubiquitinases
por: Klonisch, Thomas, et al.
Publicado: (2023)

Chimeric RXFP1 and RXFP2 Receptors Highlight the Similar Mechanism of Activation Utilizing Their N-Terminal Low-Density Lipoprotein Class A Modules
por: Bruell, Shoni, et al.
Publicado: (2013)

Elucidation of relaxin-3 binding interactions in the extracellular loops of RXFP3
por: Bathgate, Ross A. D., et al.
Publicado: (2013)

PDK2-mediated alternative splicing switches Bnip3 from cell death to cell survival
por: Gang, Hongying, et al.
Publicado: (2015)

High Mobility Group A2 protects cancer cells against telomere dysfunction
por: Natarajan, Suchitra, et al.
Publicado: (2016)

Claudin 1 Is Highly Upregulated by PKC in MCF7 Human Breast Cancer Cells and Correlates Positively with PKCε in Patient Biopsies()
por: Blanchard, Anne A., et al.
Publicado: (2019)

Maternal smoking and high BMI disrupt thyroid gland development
por: Filis, Panagiotis, et al.
Publicado: (2018)

Evidence that RXFP4 is located in enterochromaffin cells and can regulate production and release of serotonin
por: Fernando, Shalinda J.A., et al.
Publicado: (2023)

Brain Microvascular Pericytes—More than Bystanders in Breast Cancer Brain Metastasis
por: Ippolitov, Danyyl, et al.
Publicado: (2022)

Aberrant HMGA2 Expression Sustains Genome Instability That Promotes Metastasis and Therapeutic Resistance in Colorectal Cancer
por: Campos Gudiño, Rubi, et al.
Publicado: (2023)

Relaxin-3/RXFP3 Signaling and Neuroendocrine Function – A Perspective on Extrinsic Hypothalamic Control
por: Ganella, Despina E., et al.
Publicado: (2013)

Gesture-controlled interactive three dimensional anatomy: a novel teaching tool in head and neck surgery
por: Hochman, Jordan B, et al.
Publicado: (2014)

Relaxin Receptor RXFP1 and RXFP2 Expression in Ligament, Tendon, and Shoulder Joint Capsule of Rats
por: Kim, Jae Hyung, et al.
Publicado: (2016)

Modulation of Wnt/β-catenin signaling promotes blood-brain barrier phenotype in cultured brain endothelial cells
por: Laksitorini, Marlyn D., et al.
Publicado: (2019)

Complement 1q/Tumor Necrosis Factor-Related Proteins (CTRPs): Structure, Receptors and Signaling
por: Schanbacher, Constanze, et al.
Publicado: (2023)

Inhibitor of DNA Binding 2 Inhibits Epithelial-Mesenchymal Transition via Up-Regulation of Notch3 in Breast Cancer
por: Wen, Xiao-Fen, et al.
Publicado: (2018)

Complement C1q as a Potential Biomarker for Obesity and Metabolic Syndrome in Chinese Adolescents
por: Yang, Xuelian, et al.
Publicado: (2020)

Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway via Depletion of Isoprenoids in Tumor Cells
por: Alizadeh, Javad, et al.
Publicado: (2017)

C1q Complement/Tumor Necrosis Factor-Associated Proteins in Cardiovascular Disease and COVID-19
por: Xie, Yaoli, et al.
Publicado: (2021)

Relaxin family peptide receptors Rxfp1 and Rxfp2: mapping of the mRNA and protein distribution in the reproductive tract of the male rat
por: Filonzi, Marcelo, et al.
Publicado: (2007)

Changes in Knee Laxity and Relaxin Receptor Isoforms Expression (RXFP1/RXFP2) in the Knee throughout Estrous Cycle Phases in Rodents
por: Dehghan, Firouzeh, et al.
Publicado: (2016)

Peri-conceptional changes in maternal exposure to sewage sludge chemicals disturbs fetal thyroid gland development in sheep
por: Hombach-Klonisch, Sabine, et al.
Publicado: (2013)

Genes of the Ubiquitin Proteasome System Qualify as Differential Markers in Malignant Glioma of Astrocytic and Oligodendroglial Origin
por: Vriend, Jerry, et al.
Publicado: (2022)

Sex-Steroid Regulation of Relaxin Receptor Isoforms (RXFP1 & RXFP2) Expression in the Patellar Tendon and Lateral Collateral Ligament of Female WKY Rats
por: Dehghan, Firouzeh, et al.
Publicado: (2014)

Serelaxin alleviates cardiac fibrosis through inhibiting endothelial-to-mesenchymal transition via RXFP1
por: Wilhelmi, Tim, et al.
Publicado: (2020)

Plasma Complement C1q/tumor necrosis factor-related protein 15 concentration is associated with polycystic ovary syndrome
por: Vatannejad, Akram, et al.
Publicado: (2022)

ML290 is a biased allosteric agonist at the relaxin receptor RXFP1
por: Kocan, Martina, et al.
Publicado: (2017)

Molecular Basis for Defining the Pineal Gland and Pinealocytes as Targets for Tumor Necrosis Factor
por: Carvalho-Sousa, Claudia Emanuele, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_ek5oo86245t10iu6k74p8091ul